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Dysfunction of Mitochondrial Ca2+ Regulatory Machineries in Brain Aging and 2022.11.06해당카페글 미리보기
either gene highly related to PD (Narendra and Youle, 2011; Pickrell and Youle, 2015). Dopaminergic neuron-specific mitochondrial Ca2+ imaging with mito-GCaMP, a mitochondria-targeted GECI, in Drosophila PD models revealed elevated...
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Re: The Hallmarks of Aging 2022.10.26해당카페글 미리보기
sirtuin gene of these organisms, named Sir2, had a remarkable longevity activity (Guarente, 2011). Overexpression of Sir2 was first shown to extend replicative lifespan in Saccharomyces cerevisiae (Kaeberlein et al., 1999), and...
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Re: Re: Re: 글루타치온이 막망 상피세포를 치료하는 효과 2022.09.15해당카페글 미리보기
associated gene profiles of Cys2 starved and 1000 µM BSO and 10 µM erastin-treated ARPE-19 cells. Total RNA was extracted at 24 h post treatment and assayed on BGISEQ-500 RNA-Seq Full size image Next, SA-β-Gal staining was performed to...
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persistent antigen stimulation - T cell의 역할, 분화, PCA 2022.10.17해당카페글 미리보기
40, 41). As a result, depending on their level of expression on the cell surface, CTLA-4 may interfere with CD80/CD86...Several more inhibitors, such as lymphocyte activation gene 3, and V-domain Ig suppressor of T lymphocyte activation...
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Chicxulub crater 2022.10.23해당카페글 미리보기
surface expression of a zone of preferential groundwater flow, moving water from a recharge zone in the south to the coast through a karstic aquifer system.[13]: 4 [65] From the cenote locations, the karstic aquifer is clearly related to...
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Spider silk 2022.10.09해당카페글 미리보기
and Expression of Synthetic Genes Encoding Spider Dragline Silk" First successful synthesis of Spider silk by E. coli. 1998 Arcidiacono, S., Kaplan, D.L. et al.[99] "Purification and characterization of recombinant spider silk expressed...
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Re: Re: vitamin d 장염증을 치료하는 효과 2022.09.15해당카페글 미리보기
large intestine (31), whereas the CDX2 promoter directs Cre recombinase expression only in colonic epithelial cells. The CDX2-Cre mice have been used to conditionally delete Apc gene from colonic epithelial cells (32). Mice that carry...
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Nutrient Sensing Mechanisms and Pathways 2022.10.30해당카페글 미리보기
the expression of enzymes involved in the cholesterol biosynthetic pathway, from a constitutively bound complex on the endoplasmic reticulum (ER). The cholesterol-sensing protein SCAP (SREBP1 cleavage activating protein) directly binds...
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Re: The Impact of Dietary Sphingolipids on Intestinal Microbiota and Gastro 2022.10.11해당카페글 미리보기
the expression of cathelicidin antimicrobial peptide when the epidermis is under stress, i.e. in response to attack of microbial pathogens (133). At the host neutrophils plasma membrane, LacCer accounts for 70% of glycosphingolipids...
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Re: Re:Re: 미토콘드리아 기능부전 운동- 알츠하이머를 치료하는 방법 2022.09.21해당카페글 미리보기
related gene 7 (Atg7), in the APP (Swedish mutation) transgenic mice. However, these events are associated with toxic intracellular accumulation of Aβ, which likely causes neurodegeneration together with amyloidosis and memory deficit...