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Re: The Aging Stress Response and Its Implication for AMD Pathogenesis 2022.10.09해당카페글 미리보기
aspects of age-related stress responses. Autophagy activation is closely associated with nutrient status and various other stimuli, such as energy stress, endoplasmic reticulum (ER) stress, pathogen- and danger-associated molecular...
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Re: The Impact of Dietary Sphingolipids on Intestinal Microbiota and Gastro 2022.10.11해당카페글 미리보기
differences in SL content and composition, we suggest that dietary SLs contribute to the regulation of inflammatory stimuli. Therefore, elucidating intestinal SL pathways and effector metabolism is crucial for identifying novel key...
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Re: Nutritional Regulation of Muscle Stem Cells in Exercise and Disease 2022.10.28해당카페글 미리보기
Human skeletal muscle is a remarkedly plastic tissue that has a high capacity to adapt in response to various stimuli. These adaptations are due in part to the function of muscleresident stem/progenitor cells. Skeletal muscle...
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Re: The chromatin landscape of cellular senescence 2022.10.15해당카페글 미리보기
in regions called LADs. In cellular senescence, conserved and distinct features are observed depending on the stimuli. Shared features include SADS formation and the loss of interaction with the nuclear periphery or LADs detachment. SAHF...
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♣ 세상(世上)은 보는대로 있다.(The world is as it is seen.) ♣ 2022.07.31해당카페글 미리보기
등의 중간에 삽입된 기악곡.)에 따라 달라 진다.(Therefore, the brain selectively accepts only a few of the many stimuli. The standard of choice depends on the then brain's TUNE.) 정말 그 모든 걸 다 받아들여지게 된다 면 나같이 머리나쁜 사람...
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Senolytic drugs: from discovery to translation 2022.10.03해당카페글 미리보기
28, 29, 85]. Our hypotheses upon which senolytic drug discovery was based were: 1) Senescent cells can resist apoptotic stimuli, implying increased pro‐survival ‒ anti‐apoptotic defences and 2) In some respects, senescent cells are...
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Diverse Roles of Cellular Senescence in Skeletal Muscle Inflammation, Regen 2022.10.07해당카페글 미리보기
muscle function by increasing muscle mass and oxygen supply. These effects of exercise are induced by a complex of stimuli on skeletal muscle, including mechanical stress, oxidative stress, changes in the AMP:ATP ratio, an increase in...
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Re: Targeting Mitochondrial Biogenesis with Polyphenol Compounds 2022.10.07해당카페글 미리보기
fusion, fission, and mitophagy events [6]. The biogenesis of mitochondria is extremely plastic in response to environmental stimuli, developmental signals, and cellular energy demand [7] and requires mitochondrial DNA (mtDNA) replication...
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Neutrophils: mediating TelOxidation and senescence 2022.10.15해당카페글 미리보기
play critical roles in aging. One such process is cellular senescence, which is triggered in response to numerous stimuli, such as telomeric DNA shortening, DNA damage, and oncogenic stresses (Gorgoulis et al, 2019). Cellular senescence...
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The Leaky Gut: Mechanisms, Measurement and Clinical Implications in Humans 2022.10.10해당카페글 미리보기
The Intestinal Barrier The intestinal barrier is a dynamic entity interacting with and responding to various stimuli. It consists of multiple elements. In the lumen, there is degradation of bacteria and antigens by bile, gastric acid...