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Re: Regulation of Intestinal Barrier Function by Microbial Metabolites 2022.10.09해당카페글 미리보기
acid, 5-hydroxyl indole, indoxyl sulfate, N-acetyltryptophan, indoxyl sulfate, serotonin, melatonin, melatonin 6-sulfate) E. coli, C. sporogenes •Antioxidant. •Neuroprotection and cytoprotection. •Intestinal barrier regulation...
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Cardiac Myocyte Cell Cycle Control in Development, Disease and Regeneration 2022.10.22해당카페글 미리보기
2F6 Transcription factor for cell cycle genes G1-S ++ + − (155) N-Myc Transcription factor for cell cycle genes G1-S-G2M ++ +/− − (156) c-Myc Transcription factor for cell cycle genes G1-S-G2M ++ + − (142,202) Open in a separate...
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Re: Re: Re: 글루타치온이 막망 상피세포를 치료하는 효과 2022.09.15해당카페글 미리보기
organelles (e.g., lysosomes) and constitutes a redox-active liable iron pool, which regulates programmed cell death including ferroptosis42. Since DFO is membrane impermeable and accumulates in lysosomes18, we believe that it protects...
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Re: The chromatin landscape of cellular senescence 2022.10.15해당카페글 미리보기
K20me3 [32], with the facultative heterochromatin mark H3K27me3 lining its periphery [33]. This phenotype has been extensively reviewed elsewhere, but does not appear to be a universal feature of all types of senescent cells [34]. Figure...
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8/25일 주요이슈점검 2022.08.25해당카페글 미리보기
배당 20% 늘어 * 순이익 줄어도 배당 늘렸다…뿌리 내리는 주주환원 * 금융주 배당수익률 '고공행진'…증시 흔들릴수록 매력 더 커져 * 삼성디스플레이 최주선 "8세대 IT용 OLED 라인 투자…2024년 가동 목표" * 테슬라·아마존 로봇 총력전…삼성도...
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The Leaky Gut: Mechanisms, Measurement and Clinical Implications in Humans 2022.10.10해당카페글 미리보기
Tween-20] induce secretion of mucus.[23] In fact, bile salts impact the ability of mucus to serve as a barrier to hydrophilic and lipophilic compounds.[24] Secretion of mucus is a prelude to the epithelial damage that leads to colonic...
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Diverse Roles of Cellular Senescence in Skeletal Muscle Inflammation, Regen 2022.10.07해당카페글 미리보기
2F3 activation or c-Myc inhibition is DDR-independent and involves p16INK4a and p19ARF (Lazzerini Denchi et al., 2005). Another DDR-independent inducer of cellular senescence is BRAF (V600E), which activates senescence through a...
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Senolytic drugs: from discovery to translation 2022.10.03해당카페글 미리보기
19, 20, 21, 22, 23, 24]. 노화 세포는 염증, 섬유증, DNA 손상, 단백질 응집체의 발달, 자가포식 실패, 지방독성, 미토콘드리아 기능 장애, NAD+의 고갈, ROS 생성 및 줄기, 전구 세포 및 면역 세포 기능 장애에 기여 Cellular senescence Cellular...
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Re: Reprogramming the Epigenome With Vitamin C 2022.10.09해당카페글 미리보기
over 20 α-KGDDs in humans that hydroxylate and remove methyl groups from lysines in histones (Klose et al., 2006). Histone demethylation is catalyzed by the Jumonji C (JmjC)-catalytic domain to produce a highly reactive oxoferryl...
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7 Pillars OF Aging 2014년 2022.10.08해당카페글 미리보기
Sierra20 Author information Copyright and License information Disclaimer The publisher's final edited version of this article is available at Cell Go to: Abstract Mammalian aging can be delayed with genetic, dietary and pharmacologic...