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Re: 해독과 생체전환에 대한 기능의학적 접근 2020.05.14해당카페글 미리보기
with previous findings in HeLa cell cultures. The presence of dithiols, either DTT or dihydrolipoate (the metabolite of LA), increased the effects of mercury ions on glutathione concentrations in hepatoma cells, whereas monothiols such...
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Re:Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s disease - 2019 네이처 논문 2020.02.25해당카페글 미리보기
after 15 min (point of maximal levodopa bioavailability in rats22). Plasma levels of levodopa/carbidopa and its metabolite dopamine were measured by HPLC-ED, while relative abundance of the tdc gene within the small intestinal microbiota...
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Re: Immunomodulatory Effects of Diet and Nutrients in Systemic Lupus Erythe 2021.03.29해당카페글 미리보기
the other amino acids, in case-controlled studies (54, 55), lower levels of tryptophan and higher levels of kynurenine (a metabolite of tryptophan) with activation of the kynurenine pathway were detected in patients with SLE. Indeed, an...
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Re: 비타민 D의 항암효과 Nature 논문 2020.02.01해당카페글 미리보기
cancer. Vitamin D, as a prohormone, undergoes two-step metabolism in liver and kidney to produce a biologically active metabolite, calcitriol, which binds to the vitamin D receptor (VDR) for the regulation of expression of diverse genes...
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Re:Terpenes and terpenoids 2020.03.04해당카페글 미리보기
to the fungal kingdom have become proficient at exploiting this broad chemical synthesis platform for complex metabolite production. Herein, we are discussing some of the recently published bioactive meroterpenes (Table 6). Figure 7...
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Re: 단쇄지방산 중 뷰티르산의 항염증, 항암효과 2020.10.12해당카페글 미리보기
pathways, including the vagus nerve, neuroimmune pathways, and neuroendocrine pathways (118, 119). As a microbial metabolite, butyrate is capable of exerting its effects on host metabolism indirectly by acting through the gut-brain axis...
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Re: Re: 콜린 보충제의 알츠하이머 치매치료 효과 연구 2020.08.22해당카페글 미리보기
et al., 2019). Notably, choline converts Hcy to methionine through the donation of methyl groups by choline's metabolite, betaine (Zeisel, 2017). Thus, it is tempting to speculate that the reduced Aβ levels in APP/PS1 mice exposed to...
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Re:단쇄지방산 중 아세테이트의 식욕조절 기전 2020.10.12해당카페글 미리보기
hypothalamus under appetite stimulation22. In order to evaluate the contribution of potential variations in total metabolite content to the 13C incorporation profiles, we acquired 1H HR-MAS spectra for the same biopsies we used for the...
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세로토닌 2019.06.24해당카페글 미리보기
of the central nervous system, because it does not cross the blood–brain barrier.[9] However, tryptophan and its metabolite 5-hydroxytryptophan (5-HTP), from which serotonin is synthesized, does cross the blood–brain barrier. These...
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실데나필 2020.03.31해당카페글 미리보기
names of their products. Detection in biological fluids Sildenafil and/or N-desmethylsildenafil, its major active metabolite, may be quantified in plasma, serum, or whole blood to assess pharmacokinetic status in those receiving the drug...