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Re:Re:A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis 2020.02.13해당카페글 미리보기
the cell culture media using CytoTox96® Non-Radioactive Cytotoxicity Assay according the manufacturer's instructions (Promega Corp). Mitochondria preparations and ATP measurements Mitochondria isolation and ATP measurements were...
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Re:Re:Intracellular Protein Degradation and Its Therapeutic Implications 2020.04.13해당카페글 미리보기
Kenneth C. Anderson DOI: 10.1158/1078-0432.CCR-05-2305 Published December 2005 Article Figures & Data Info & Metrics PDF Lysosomal and ubiquitin (Ub)-mediated protein degradation are two mechanisms for intracellular protein catabolism...
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Re:미토콘드리아기능 회복을 위한 철분-황의 관계에 대한 탐구!! 2019.12.31해당카페글 미리보기
fission, fusion, and mitochondrial morphology are regulated by a dedicated protein machinery (recently reviewed [4]). Go to: 2. Mitochondrial Function Mitochondria carry out diverse cellular functions and play crucial roles in cellular...
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Re:Re:Current perspectives on statins as potential anti-cancer therapeutics: clinical outcomes and underlying molecular mechanisms 2019리뷰논문 2020.02.10해당카페글 미리보기
lysosome fusion. Mevastatin also was reported to increase HDACi LBH589-induced cell death in triple-negative breast cancer (TNBC) cells suggesting co-treatment with mevastatin and LBH589 activated LKB1/AMPK signaling and subsequently...
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Re:Thymosin alpha1의 면역세포활성화 기전탐구!! 2020.02.03해당카페글 미리보기
NK-cell activity and prevents tumor progression in mice immunosuppressed by cytostatics or X-rays. Cancer Immunol...1983;15:78–83. doi: 10.1007/BF00199694. [PubMed] [CrossRef] [Google Scholar] 13. Matteucci C, et al. Thymosin alpha 1...
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Re: Heat Shock Proteins in Cancer Immunotherapy 2020.10.09해당카페글 미리보기
human fusion protein vaccine composed of HSP70-HPV16 oE7 antigen was shown to elicit effective CD8+ antitumor cell-mediated response [50]. Another study by Abkin et al. showed that the purified HSP70-based gel diffused effectively...
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Re:Exercise is mitochondrial medicine for muscle 2020.06.03해당카페글 미리보기
of fusion in which mitofusin 1/2 (Mfn) and optical atrophy 1/2 (Opa) tether and ligate the outer and inner membranes, respectively, to fuse the joining organelle into the network. As discussed in the text, defects in several of these...
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Re: 연관 논문 2010.11.12해당카페글 미리보기
A.C. Hergarden, D.A. Andersson, S.W. Hwang, P. McIntyre, T. Jegla, S. Bevan, A. Patapoutian, ANKTM1, a TRP-like channel...nociceptive neurons, is activated by cold temperatures, Cell 112 (2003) 819-829; S. Jordt, D. Julius, Molecular...
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Re:Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies 2020.02.17해당카페글 미리보기
breakage–fusion–bridge cycles in which two sister chromatids lacking telomeres fuse together, forming a bridge with a chromatin connection. During anaphase, the sister chromatids are drawn apart owing to movement towards opposite poles...
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Re:The significant role of interleukin-6 and its signaling pathway in the immunopathogenesis and treatment of breast cancer 2020.01.29해당카페글 미리보기
and c-Jun [61,62]. It has been shown that autocrine release of IL-6 by MCF-7 cells enhances their invasion capacity to the extracellular matrix [63]. The loss of function in the E-cadherin, a membrane adhesion molecule, which leads to...