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Re: SAM-e 보충제의 간기능 보호, 항암효과 2020.10.12해당카페글 미리보기
AMPK and LKB1 are traditionally thought of as metabolic tumor suppressors, they induce hepatocyte proliferation, via HuR cytoplasm translocation and stabilization of cyclin D1 and cyclin A expression, following hepatocyte growth factor...
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Re:Re: 만성 미세염증(chronic micro-inflammation)을 이해하기 위한 mast cell의 기능탐구 2019.12.26해당카페글 미리보기
links the FcεR1 molecules, and Lyn tyrosine kinase phosphorylates the ITAMs in the FcεR1 β and γ chain in the cytoplasm. Upon the phosphorylation, the Syk tyrosine kinase gets recruited to the ITAMs located on the γ chains. This...
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Re: Re: Autophagy: Renovation of Cells and Tissues - cell 리뷰논문 2020.08.26해당카페글 미리보기
복용하는 상황에서도 간에서는 대략 시간당 1-1.5%의 세포단백질이 이화되는 과정을 거침. Macroautophagy: A portion of cytoplasm, including organelles, is enclosed by an isolation membrane (also called phagophore) to form an autophagosome...
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Re: The sirtuin class of histone deacetylases: Regulation and roles in lipi 2020.11.09해당카페글 미리보기
In fact, although it is mainly localized in the nucleus, under specific conditions SIRT1 can shuttle to the cytoplasm 16 controlling not only nuclear but also cytoplasmic target proteins. SIRT2, highly expressed in heart, brain, and...
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Re:Mitochondrial metabolism and cancer - 2017 nature review 2020.01.16해당카페글 미리보기
82. Besides fueling the oxidative mode of the TCA, citrate can also be converted into acetyl-CoA for export to the cytoplasm and nucleus4,81, where it can either be employed for fatty acid and cholesterol synthesis (to support the...
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Re: nerve injury - neuropraxia, axonotmesis, neurotmesis 2020.06.20해당카페글 미리보기
before macrophages arrive at the injury site, myelin is fragmented and myelin debris and lipid droplets are found in the cytoplasm of Schwann cells, indicating phagocytic activity before macrophages arrive. Schwann cell activity includes...
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Re: 비타민 D는 섬유아세포의 과도한 콜라겐합성을 억제하여 섬유화를 방지 2020.09.18해당카페글 미리보기
detected in the cell culture. After 30 min incubation with 1,25D, VDR expression was clearly increased in the cytoplasm and nuclear compartment. A similar observation was made at 1 and 5 h (Fig. 1). By contrast, after 24 h, 4 and 7 days...
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암과 노화에서의 SIRT1의 기능 - histone deacetylation의 개념포함 2020.10.15해당카페글 미리보기
물질로 식품은 물론 화장품에 이르기까지 인기를 끌고 있다 SIRT3에 대하여 다른 논문 정리 SIRT은 포유동물의 세포핵, cytoplasm, 미토콘드리아에 존재하는 7개의 sirt 단백질 known as class 3 deacetylase SIRT3는 cancer genetics, 노화, 퇴행성 신경...
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Re: 메벤다졸의 항암효과 - 2019년 cancers 리뷰논문 2020.10.09해당카페글 미리보기
similar DEF50s (1.34–1.53). Mebendazole hindered DNA repair through inhibition of the trafficking of DDRp from the cytoplasm to the nucleus. Two proteins mediators of DSB repair, Chk2 and Nbs1, were evaluated: in GL261 cells the EC50...
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Re: An Apoptotic ‘Eat Me’ Signal: Phosphatidylserine Exposure - cell 리뷰논문 2020.09.02해당카페글 미리보기
category. The second category consists of proteins at the ER that translocate dolichol-conjugated sugars from the cytoplasm to ER lumen for N-glycosylation of proteins. ATPases belonging to the ABC transporter family are flippases of the...