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Re: 메벤다졸의 항암효과 - 2019년 cancers 리뷰논문 2020.10.09해당카페글 미리보기
to the nucleus. Two proteins mediators of DSB repair, Chk2 and Nbs1, were evaluated: in GL261 cells the EC50 for cytoplasmic sequestration of Chk2 (31 nM) and Nbs1 (25 nM) was very similar to the EC50 for radiosensitization (35 nM) and...
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Re: The Klotho proteins in health and disease - 2018 네이처 리뷰 2020.11.11해당카페글 미리보기
encodes the secreted isoform contains a stop codon upstream of exons 4 and 5, which encode the transmembrane and cytoplasmic domains. However, this truncated protein isoform has thus far not been detected in blood. b | Membrane αKlotho...
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Re:Mitochondrial metabolism and cancer - 2017 nature review 2020.01.16해당카페글 미리보기
associated with intense proliferation) or used for acetylation reactions, which regulate transcription as well as cytoplasmic processes including autophagy36,83,84. In line with this notion, the enzyme that converts citrate into acetyl...
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Re:Re: 만성 미세염증(chronic micro-inflammation)을 이해하기 위한 mast cell의 기능탐구 2019.12.26해당카페글 미리보기
that are similar to Ig. One transmembrane domain contains an aspartic acid residue, and one contains a short cytoplasmic tail.[18] The β chain contains, a single immunoreceptor tyrosine-based activation motif ITAM, in the cytoplasmic...
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Re: 운동은 NK cell의 조절을 통해 항암효과 2020.01.05해당카페글 미리보기
kill infected or transformed cells. There are several ways in which NK cells can achieve this: (i) by releasing cytoplasmic granules containing perforin and granzymes that leads to target cell lysis (cytotoxicity); (ii) via death...
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Re:Re:Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation - 2016 네이처 논문 2020.03.25해당카페글 미리보기
of lysosomal and autophagic target genes. MTOR can decrease lysosomal function by phosphorylating TFEB to cause cytoplasmic retention and reduce lysosomal gene expression.17 We observed that Hcy treatment increased TFEB cytoplasmic...
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Re: The caspase‐activated DNase: apoptosis and beyond 2020.09.02해당카페글 미리보기
noncell autonomous signaling of apoptotic cells to differentiation has not been examined. DNA fragmentation and cytoplasmic release of histones is observed in the apoptotic myoblasts that accompany differentiation [40]. As such it will...
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Re: Re: Re: Role of advanced glycation end products in cellular signaling 2020.08.23해당카페글 미리보기
CD4+, CD8+), endothelial cells, mesangial cells, fibroblasts, smooth muscle cells, neuronal cells Highly acidic cytoplasmic domain, a single transmembrane domain, extracellular domain consisting of VC1-ligand binding domain and C2...
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두개인두종 최신지견 Medscape.com (영문) 2012.05.20해당카페글 미리보기
and fate determination. Immunohistochemistry for beta-catenin in adamantinomatous craniopharyngiomas showed an abnormal cytoplasmic and nuclear accumulation. The normal membranous staining was present in adamantinomatous and papillary...
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항생제의 작용기전과 종류 2007.12.17해당카페글 미리보기
항생제의 작용기전 * 항생물질의 작용점 종 류 Cell wall(세포벽)을 합성저해 penicillin, cephalosorin, vancomycin Cytoplasmic membrane (세포막)저해 poly-myxin, colistin, amphotericin, imidazole Ribosome 합성저해 kanamycin, aminoglycoside...