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Re:Re:Glial Cells(astrocyte, microglia, oligodendrocyte) and Their Function in the Adult Brain 2020.02.19해당카페글 미리보기
that target the astrocyte population under physiological conditions. To specifically deplete the astrocyte population in the adult healthy brain, again both pharmacological as well as genetic approaches are available and have been used...
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Re: Recent advances in understanding and managing cholesterol gallstones - 번역해야 2019.11.30해당카페글 미리보기
been detected in CCK knockout mice166. Future perspectives: from therapy to prevention The majority of patients with gallstone disease remain asymptomatic throughout their life167,168 and should be managed with watchful waiting40. If...
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Re:Re:토마스 사이프리드 교수의 Ketogenic 식이요법으로 뇌종양 치료 사례논문 2020.02.09해당카페글 미리보기
was detected (Figure (Figure5).5). An MRI, performed on July 22, was stable over the comparison time from February 24 with no clear evidence of disease recurrence. At that time, the patient weighed 50 kg (110 pounds, BMI 20.0 kg/m2), was...
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케톤체(BHB, 베타-하이드로뷰티레이트) 대하여 - 2019 리뷰논문 2020.11.21해당카페글 미리보기
into target tissues or its intracellular movement remain to be identified. BHB Chirality BHB is a chiral molecule at the 3′ hydroxyl group, an important feature in consideration of its signaling activities and possible therapeutic...
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Re:The role of the insulin-like growth factor-1 system in breast cancer 2020.01.28해당카페글 미리보기
distant target sites for BrCa metastasis. Hiraga et al. showed that bone derived IGF-1 stimulates proliferation and bone localization of breast cancer cells in vivo through activation of AKT and recruitment of transcription factor NF-kB...
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off label 약물 - 피르비늄의 항암효과 2019.11.28해당카페글 미리보기
does not cause significant apoptotic cancer cell death under normal physiological conditions; however, massive cell death occurs in response to pyrvinium when subjected to worse conditions such as starvation, genotoxic insult or pathogen...
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Re: 암관련 섬유아세포가 암전이 과정의 기전과 치료법 2020.02.01해당카페글 미리보기
are not intrinsically resistant in vitro but maintain the ability to reproduce resistant tumors upon re-injection, hinting at the involvement of cancer-derived signals activating the surrounding stroma. Indeed, resistant cells display a...
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Re:Oligo-Fucoidan prevents IL-6 and CCL2 production and cooperates with p53 to suppress ATM signaling and tumor progression - nature 논문 2020.01.09해당카페글 미리보기
its target gene, superoxide dismutase25; and suppressing the transforming growth factor β (TGF-β)/Smad pathway26, which prevents reactive oxidative species (ROS) generation in cancer cells and ROS release into the TME27. These results...
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Re:Zinc enhances the cellular energy supply to improve cell motility and restore impaired energetic metabolism in a toxic environment induced by OTA 2020.05.28해당카페글 미리보기
was detected by Western blotting. (D) The phosphorylation degree of AMPK in Thr172 was normalized to AMPK expression. (E) The phosphorylation degree of ACC in Ser79 was normalized to ACC expression. The values are expressed as the means...
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The Economist Articles for Oct. 1st Week : Oct. 4th(Interpretation), Oct. 5th(Discussion) 2014.09.26해당카페글 미리보기
he detected hypocrisy in the West’s treatment of Scotland’s referendum and that in his territory. In the run-up to Scotland’s referendum EU officials strained to avoid taking a position on the consequences of a “yes” (while quietly...