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senolytics, 세포 노화의 처리 2022.10.03해당카페글 미리보기
species. Cellular senescence takes longer to become established than other cell fates, such as replication, differentiation, apoptosis or necrosis. From initiation to the attainment of a completed state of cellular senescence takes from...
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Re: Turning back time with emerging rejuvenation strategies 2022.10.26해당카페글 미리보기
aged mice, reversing the age-dependent decline in stem cell activation and number and improving their age-associated differentiation bias16,17. Since then, heterochronic parabiosis has been shown to enhance muscle, liver, brain and heart...
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MSC - Osteoblast, bone lining cell - osteocyte, 뼈 senescent 그림 이해 2022.10.08해당카페글 미리보기
contacts through the interactions between EFNB2-EPHB4, FAS-FASL and NRP1-SEMA3A to regulate cell proliferation, differentiation, and survival. (2) Osteoclast-mediated bone resorption releases TGF-β and IGF-1 from bone matrix to induce...
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Re: The Impact of Dietary Sphingolipids on Intestinal Microbiota and Gastro 2022.10.11해당카페글 미리보기
promising candidates for treatment of immune-mediated diseases and as predictive biomarkers. SLs Influence Cell Differentiation Along the Crypt-Villus Axis SLs are found throughout the whole GI tract, but preferably located in the apical...
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Cell cycle control in the kidney 2022.10.22해당카페글 미리보기
B1 are not detectable [14, 15]. These changes are associated with podocyte exit from the cell cycle and their differentiation into mature podocytes expressing podocyte marker proteins, such as WT-1 or podocalyxin [14, 15]. The...
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Cardiac Myocyte Cell Cycle Control in Development, Disease and Regeneration 2022.10.22해당카페글 미리보기
of cardiac myocytes in utero, their cell cycle exit in the perinatal period and the permanent arrest (terminal differentiation) in adult myocytes. The recent identification of cardiac progenitor cells capable of giving rise to cardiac...
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Neuronal cell cycle: the neuron itself and its circumstances 2022.10.22해당카페글 미리보기
69 Evidence from our laboratory indicates that these newly formed neurons, defined by the expression of specific differentiation markers,69 re-enter into the cell cycle during their migration to the ganglion cell layer in response to the...
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Cellular Senescence in Brain Aging 2022.10.07해당카페글 미리보기
from A-T (Ataxia telangiectasia) reprogrammed fibroblasts. We showed that A-T NPCs, obtained through neural differentiation of iPSCs in 5% oxygen, possessed some features of senescence, including increased activity of SA-β-gal...
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Re:Epigenetic Regulation of Genomic Stability by Vitamin C 2022.10.09해당카페글 미리보기
DNA imprinting and X-chromosome inactivation that in combination instruct embryonic development and cellular differentiation (Guo et al., 2014). DNA methylation also plays direct and indirect roles in maintaining genomic stability. Both...
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Re: The chromatin landscape of cellular senescence 2022.10.15해당카페글 미리보기
a role in transcriptional regulation as evidenced by the fact that it features prominently during stem cell differentiation [61] and early B cell development [62]. Box 1 Genome-wide chromosome conformation capture High-resolution maps of...