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Cell cycle control in the kidney 2022.10.22해당카페글 미리보기
future drug options for cell cycle modulation in kidney disease. THE CELL CYCLE AND ITS CHECKPOINTS The cell cycle is a unidirectional pathway that, if completed, can lead to cell division (Figure 1). The cell cycle involves four tightly...
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Neuronal cell cycle: the neuron itself and its circumstances 2022.10.22해당카페글 미리보기
for drug development. Biochim Biophys Acta 2007; 1772:503-8; PMID:17223322 [PubMed] [Google Scholar] 53. Verdaguer E, Susana Gde A, Clemens A, Pallàs M, Camins A. Implication of the transcription factor E2F-1 in the modulation of...
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Re: Targeting the molecular & cellular pillars of human aging with exercise 2022.10.08해당카페글 미리보기
as drug interventions in the secondary prevention of coronary heart disease (CHD) [[3]], and even outperforms standard metformin treatment in preventing type 2 diabetes [[4]]. In overweight/obese middle-aged adults with impaired fasting...
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Age-related alterations and senescence of mesenchymal stromal cells 2022.10.08해당카페글 미리보기
targeted drug with high activity, specificity, potency and bioavailability in the absence of toxicity for long-term use in predominantly older adults (Oo et al., 2018). In recent years, a particular focus has been for treatments that can...
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How evolutionary principles improve the understanding of human health and d 2022.11.19해당카페글 미리보기
fear induced is excessive or if it is inappropriately triggered, then a phobia may be manifest. Nesse has expanded on this class of mechanism extensively (Nesse 2005). The long historical exposure of humans to microorganisms such as...
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7 Pillars OF Aging 2014년 2022.10.08해당카페글 미리보기
and drug interventions to predict responses in human healthspan trials. Integrate human genetic and epigenetic studies with animal models Human genome association studies have identified aging-associated gene variations from either...
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Re: The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Co 2022.10.11해당카페글 미리보기
influencing drug metabolism and absorption have started to be elucidated (4, 5). Further, it was recently unveiled that the influence of the microbiota is not restricted to the GI tract; it plays a major role in the bidirectional...
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양성자세현훈 2022.09.30해당카페글 미리보기
diarrhea induced by post-operative antibiotics.[citation needed] BPPV is one of the most common vestibular disorders in people presenting with dizziness; a migraine is implicated in idiopathic cases. Proposed mechanisms linking the two...
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미국의 기대수명...큐바 보다 낮다.. 2022.09.16해당카페글 미리보기
US: drug overdoses, heart disease, chronic liver disease and cirrhosis and suicides. The corporate press also observed racial disparities. There had been progress in reducing LE differences between Black and White Americans. This was...
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Current understanding of metal ions in the pathogenesis of Alzheimer’s dise 2022.10.01해당카페글 미리보기
tau-induced synaptic toxicity [5]. To help the readers quickly understand the key points, we summarized how metal ions (Fe, Cu, Zn and Ca) are involved in AD-like neurodegeneration and memory deficits, mainly from their effects on...