카페검색 본문
카페글 본문
-
Cellular senescence: all roads lead to mitochondria 2022.10.22해당카페글 미리보기
the cell’s biology. These manifestations of the senescent phenotype are highly dependent on the cell-type, inducing stimuli and physiological context. This phenotypic and temporal heterogeneity makes it nearly impossible for the...
-
cell death를 일으키는 미토콘드리아 기능의 손상지점 - membrane permeablization 2022.10.21해당카페글 미리보기
is induced, following distinct but sometimes overlapping mechanisms. ΔΨm dissipation is promoted by proapoptotic stimuli as diverse as members of the Bcl-2 family of proteins (Bax, Bak, tBid), Ca2+ and cytosolic metabolites (all of...
-
persistent antigen stimulation - T cell의 역할, 분화, PCA 2022.10.17해당카페글 미리보기
and cytokines that attract T lymphocytes, activating them through their antigenic receptors (1). Although innate immune stimuli may contribute to chronic inflammation, the adaptive immune system may also be involved because T lymphocyte...
-
과학기술을 위한 인공지능(AI) 2022.11.16해당카페글 미리보기
한편, AI의 7가지 유형은 다음에 열거된 바와 같다: 1. Reactive Machines: Has no memory, only responds to different stimuli 2. Limited Memory: Uses memory to learn and improve its responses 3. Theory of Mind: Understands the needs of other...
-
Re: Intercellular mitochondrial transfer as a means of tissue revitalizatio 2022.10.26해당카페글 미리보기
cells from the tumor microenvironment (TME) that undergo dynamic progression involving resistance to different stimuli and therapies.79,80,81 Mitochondrial transfer between tumor cells and other cells within the TME is also an important...
-
Re: cell death의 기전과 명명법 2018년 학회 2022.10.20해당카페글 미리보기
one to four BCL2 homology (BH) domains (i.e., BH1, BH2, BH3, and BH4) [29, 42, 43]. In response to apoptotic stimuli, MOMP is mediated by BCL2 associated X, apoptosis regulator (BAX), and/or BCL2 antagonist/killer 1 (BAK1; best known as...
-
Re: Hallmarks of Cellular Senescence. 2018년 리뷰논문 2022.10.24해당카페글 미리보기
the accumulation of cellular senescence [1], a state of permanent cell cycle arrest in response to different damaging stimuli [2] (Box 1). Excessive and aberrant accumulation of senescent cells in tissues can negatively affect...
-
Cell cycle control in the kidney 2022.10.22해당카페글 미리보기
global stress responses with DNA damage is p38MAPK/MK2. The p38MAPK/MK2 pathway responds to various stress-cellular stimuli, including cytokines, hyperosmolarity and UV irradiation [12] and halts the cell cycle progression in G2/M phase...
-
Cardiac Myocyte Cell Cycle Control in Development, Disease and Regeneration 2022.10.22해당카페글 미리보기
do not address the issue of whether they also mediate the inability of adult myocytes to divide in response to growth stimuli. Studies utilizing temporally regulated, cardiac-restricted Rb null are in progress to resolve this question. C...
-
Neuronal cell cycle: the neuron itself and its circumstances 2022.10.22해당카페글 미리보기
S transition and DNA synthesis. Examples of this situation are cerebellar granule neurons subjected to excitotoxic stimuli61 and cortical and hippocampal neurons subjected to hypoxia/reperfusion.62 Although terminally differentiated...