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Re: .. 글루탐산 흥분성 독성 탐구.. 치매, 파킨슨 치료...nature 2024.08.08해당카페글 미리보기
cognition, motor function and mood. Neuropsychiatry changes are caused by the dysfunction or death of specific neuronal cell types in the brain. GABAergic projections of medium-size spiny neurons (MSNs) of the neostriatum are the most...
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Re: 파킨슨 증후군 2. multiple system atrophy. 2019 nature 2024.08.02해당카페글 미리보기
any motor deficits, even after 330–400 days. Only A53T-expressing (Tg(SNCA*A53T+/+)) mice, but not others, displayed α-synuclein pathology in neurons and astrocytes in the limbic system. Interestingly, these injected mice retained...
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Re: 하지불안 증후군 약물치료 이해 논문.. 2024.07.31해당카페글 미리보기
An induction of mitochondriogenesis seems to take place in RLS; this may be the result of cellular attempts to correct metabolic insufficiency and leads to cytosolic iron deficiency. This would be consistent with the previous reports of...
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Re: glutamate receptor와 파킨슨 증상의 관계 탐구!! 2024.07.29해당카페글 미리보기
the sites of kainite subunits with low affinity (i.e., GluK1 to GluK3), which showed anticonvulsant effects without the induction of motor dysfunction [83]. In addition, glutamate receptor antagonists from a new series of 6-substituted...
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Re: 고압산소 치료. 파킨슨 병 치료 효과기전 탐구!! 2024.07.28해당카페글 미리보기
and MMP-9/2 gene expression in rats, so that improved motor function scores and increased myelinated nerve fibers.38...the key role of endoplasmic reticulum stress in the induction of neuronal apoptosis following SCI. In this regard, it...
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Re: 성상교세포의 활성.. 파킨슨 병 역할 탐구... 2024.07.24해당카페글 미리보기
either induction of autophagosome formation or inhibition of autophagosome/autolysosome degradation. Furthermore, expression of GFP-tagged, PD-causing LRRK2 mutants (R1441C, Y1699C, and G2019S) in primary mouse astrocytes has been shown...
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Re: 미세아교세포의 활성.. 파킨슨 병 병리 탐구... 2024.07.24해당카페글 미리보기
robust induction of TNF and CCR7 observed in monocyte-derived macrophages. Moreover, primary microglia produce increased CD163 and CCL18 after stimulation with dexamethasone, while the response of monocyte-derived macrophages is largely...
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파킨슨병 레보도파 효과 없을 때 대안찾기? 2022 Nature review 2024.07.21해당카페글 미리보기
systemic induction of the enzyme aromatic L-amino acid decarboxylase (AADC), leading to premature conversion of levodopa into dopamine, again limiting the bioavailability within the brain. We discuss these two mechanisms and focus on the...
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Re: 자가포식-리소좀 시스템 2020 nature 논문 . 2024.07.10해당카페글 미리보기
kinesin motor protein KIF5B41,65 binding to the PI(4,5)P2 clusters and presumably pulling on the autolysosomal membrane while moving away on microtubules65. Tubulation is facilitated by WHAMM-mediated actin formation at the autolysosome...
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AIM-174B와 AIM-120의 크기 차이 2024.07.09해당카페글 미리보기
without motor or warhead, which can be used for ground handling and loading training. Regarding its size, the standard SM-6 missile is about 21 feet (6.4 meters) long. Judging by the person standing near the missile for scale, the AIM...