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Re:History of the Selective Autophagy Research: How Did It Begin and Where Does It Stand Today? 2020리뷰논문 2020.02.15해당카페글 미리보기
PE) conjugation machineries, with Atg3, Atg4, Atg5, Atg7, Atg8, Atg10, Atg12, and Atg16; and (5) the only integral membrane protein Atg9. These Atg proteins assemble in a hierarchical fashion at the perivacuolar phagophore assembly...
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Mitochondrial calcium homeostasis as potential target for mitochondrial medicine(미토콘드리아 의학) 2020.02.15해당카페글 미리보기
2 protein family provide opportunities for possible anti-ischemic therapies (Reed, 2001), either through a gain of anti-apoptotic function or loss of pro-apoptotic function. The pharmacological strategy inhibiting mitochondrial outer...
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Re:The role of mitochondria in amyotrophic lateral sclerosis 2020.02.13해당카페글 미리보기
of inositol 1,4,5-trisphosphate receptor (IP3R) with VDAC via glucose-regulated protein 75 (Grp75), and the integral ER protein VAPB that binds to protein tyrosinephosphatase-interacting protein 51 (PTPIP51) on the OMM (Fig. 2). Among...
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Re:Mitochondrial Biogenesis in Skeletal Muscle: Exercise and Aging 2020.02.11해당카페글 미리보기
as integral membrane proteins, spanning the mitochondrial inner membrane and having domains associated with both the...space. In a manner similar to the Tom receptor complexes, Tim17 and Tim23 bind the precursor protein, prevent any...
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Re:Local Hyperthermia in Oncology – To Choose or not to Choose? 리뷰논문 2020.02.11해당카페글 미리보기
dependent protein-kinase (DNA-PK), [121] is also a radio-sensitizer. Sensitizing the classical ionizing-radiation by hyperthermia has been well-known [122], [123] for a long time, and different review articles have summarized this...
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Re:Cardiovascular Effects of Treatment With the Ketone Body 3-Hydroxybutyrate in Chronic Heart Failure Patients 2020.02.07해당카페글 미리보기
time integral, GLS, LVEF and S’max during 3-OHB infusion. The increments were not statistically significant until the infusion rate was increased to 0.09 g · kg-1 · h-1 (Table 3). Studies 3 and 4: Effect of 3-OHB Infusion on MEE in...
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Re:Re: The effects and the mechanisms of autophagy on the cancer-associated fibroblasts in cancer 2020.02.01해당카페글 미리보기
I protein conversion levels in the CAFs are higher than those in NFs. The significant levels of downregulated E-cadherin and upregulated vimentin/N-cadherin are found in the TNBC cells from the CAF group. This effect was reversed when...
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Re:아연의 항암효과 2020.01.31해당카페글 미리보기
is integral to many enzymes and transcription factors that regulate key cellular functions such as the response to oxidative stress, DNA replication, DNA damage repair, cell cycle progression, and apoptosis. In particular, several...
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케톤혁명 3-1. 암치료에 효과적인 성분 2020.01.31해당카페글 미리보기
is integral to many proteins and transcription factors which regulate key cellular functions such as the response to oxidative stress, DNA replication, DNA damage repair, cell cycle progression, and apoptosis. Zinc has been ascribed...
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Re:케톤체의 항암효과 β-hydroxybutyrate paradox 2020.01.29해당카페글 미리보기
peak integral of the respective internal standard (TSP for 1H and MDP for 31P MRS). Histology The formalin-fixed part of the tumour was embedded in paraffin wax and 3-μm sections cut de-waxed and rehydrated as standard. Slides were...