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Mitochondrial control of inflammation - 2022년 nature reviews 2022.10.20해당카페글 미리보기
PCr). ATP can be released by dying cells through lysosomal secretion and pannexin 1 (PANX1) channels, mediating both chemotactic and immunostimulatory effects on antigen-presenting cells (APCs) by binding to the purinergic receptors...
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persistent antigen stimulation - T cell의 역할, 분화, PCA 2022.10.17해당카페글 미리보기
from the bloodstream or bring them into apoptosis. Telomere loss could be stopped by inhibiting cytokines, such as TNF-α, mediating telomere shortening. T Lymphocyte Exhaustion In a viral infection or cancerous environment where there...
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Re: The chromatin landscape of cellular senescence 2022.10.15해당카페글 미리보기
of DNA damage [68]. In addition to PRC-group proteins, a long-noncoding RNA called ANRIL has an important role in mediating PRC recruitment and repression of p16 [69]. In many types of cancer, the INK4A locus is aberrantly silenced by...
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Neutrophils: mediating TelOxidation and senescence 2022.10.15해당카페글 미리보기
9): e108164. Published online 2021 Apr 20. doi: 10.15252/embj.2021108164 PMCID: PMC8090830 PMID: 33880795 Neutrophils: mediating TelOxidation and senescence Maria Sol Jacome Burbano, 1 Julien Cherfils‐Vicini, 1 and Eric Gilson Abstract...
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Re: The Impact of Dietary Sphingolipids on Intestinal Microbiota and Gastro 2022.10.11해당카페글 미리보기
still remain elusive. SLs and MicrobiotaMicrobial SL Metabolism While the importance of mammalian SL turnover for mediating various cellular processes is well recognized, mechanisms of microbial SL metabolism are not adequately...
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Re: The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Co 2022.10.11해당카페글 미리보기
vagus nerve signaling (57). Changes in enteric neuron activity perceived by the vagus nerve are essential for mediating satiety, stress, and mood (12, 58, 59). Given the close physical proximity, gut bacteria can interact with and...
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Re: The role of protein clearance mechanisms in organismal ageing and age-r 2022.10.09해당카페글 미리보기
with the consequent accumulation of undigested cargos inside the lysosome44. The molecular mechanisms mediating this demise are not fully established, although multiple studies indicate that ATG proteins, autophagy inductors and the...
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Re: Targeting Mitochondrial Biogenesis with Polyphenol Compounds 2022.10.07해당카페글 미리보기
exact molecular mechanisms of resveratrol-induced mitochondrial biogenesis remain unclear. Resveratrol's effects on mediating mitochondrial biogenesis through initiating AMP protein kinase (AMPK) have been presented by various authors...
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하문호 기초교의신학 기독론 서문 - 영문번역본 2022.10.04해당카페글 미리보기
6) The Characteristics of the intercessory and prophetic ministry 4. The Kingly Office ⑴ The concept of Christ's mediating kingship 1) Definition 2) Distinguishing between original and Mediate kingship 3) Biblical Base about mediate...
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Is Mitochondrial Dysfunction a Common Root of Noncommunicable Chronic Disea 2022.10.02해당카페글 미리보기
between mitochondrial dysfunction and obesity (40), with mitochondrial dysfunction often proposed as a critical factor mediating the progression of many obesity-related NCDs (Table 1) (41). Table 1. Tissue-specific mitochondrial...