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靑松 건강칼럼 (873)... 코로나19 사태 1000일 2022.10.22해당카페글 미리보기
opportunities), 기회가 전파로 이어질 확률(transmission probability), 인구집단 중 감염될 수 있는 사람의 평균 비율(susceptibility)을 모두 고려해 나타내게 된다. 이 지수는 감염자 1명이 몇 명을 감염시키는지 나타내는 값으로 1 이상이면 유행...
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cell death를 일으키는 미토콘드리아 기능의 손상지점 - membrane permeablization 2022.10.21해당카페글 미리보기
540) argue against the concept of necrosis as a merely accidental cell death and rather suggest that the susceptibility to undergo necrosis is partially determined by the cell (and not only by the stimulus) and that the necrotic process...
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persistent antigen stimulation - T cell의 역할, 분화, PCA 2022.10.17해당카페글 미리보기
of these diseases as well as autoimmune syndromes (103). These findings suggest that telomere loss increases susceptibility to autoimmune disease and may be a predisposing factor for age-related inflammatory disease. Restoring telomerase...
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Re: Regulation of Intestinal Barrier Function by Microbial Metabolites 2022.10.09해당카페글 미리보기
mucosal barrier. •Lack of MUC2 or O-glycan or N-glycosylation lead to severe gut barrier dysfunction and generate susceptibility to colitis. Tuft cells (small intestine, colon) •Secrete IL-25 leading to release of IL-13 from type 2...
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Gut microbiome and cellular senescence .. aging and disease 2022.10.09해당카페글 미리보기
of IECs (such as barrier functions) and ultimately contribute to increased gut permeability and enhanced susceptibility to inflammation and infections (Fig. 3). A recent analysis showed an age-dependent increase in senescent p16Inka...
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Re: The Aging Stress Response and Its Implication for AMD Pathogenesis 2022.10.09해당카페글 미리보기
life between young and older adults, such as nutrient intake and physical activity that may influence AMD susceptibility [9]. The aging stress response seems to be a prime candidate to distinguish AMD susceptibility of younger and older...
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Re:Epigenetic Regulation of Genomic Stability by Vitamin C 2022.10.09해당카페글 미리보기
DNA Damage Induces Changes in DNA Methylation and 5hmC Formation DNA methylation and oxidized mCs regulate the susceptibility of cells to genomic instability by also actively participating in sensing and repair processes upon DNA damage...
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Re: Targeting the molecular & cellular pillars of human aging with exercise 2022.10.08해당카페글 미리보기
chromosomal deterioration and has been linked to chronological aging [[25, 26]]. Telomere shortening increases susceptibility to rampant chromosomal end fusions and activates a prolonged DNA damage response, leading to the induction of...
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nature) 2002.06. Angiotensin-converting enzyme 2 is an essential regulator 2022.09.27해당카페글 미리보기
cardiovascular diseases are multifactorial in nature and disease pathogenesis is influenced by multiple genetic susceptibility loci3. In various recombinant rat models, several QTL for hypertension have been identified. ace2 maps to the...
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Re: Re:Re: 미토콘드리아 기능부전 운동- 알츠하이머를 치료하는 방법 2022.09.21해당카페글 미리보기
of SAD (Leuner et al., 2012). Furthermore, recent reports have verified that increased production of ROS and susceptibility to the opening of mitochondrial permeability transition pore (mPTP) in APP/PS1/Tau triple transgenic (3xTg) AD...