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Re: Neural plasticity in the ageing brain - nature 리뷰 2020.10.25해당카페글 미리보기
in AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid) receptor currents and is suggestive of a compensatory mechanism that increases postsynaptic sensitivity in response to the reduced medial perforant path input39,47,71...
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Lincoln Project Billboards Mocking Ivanka Trump and Jared Kushner to Stay U 2020.10.25해당카페글 미리보기
read. “If these billboards are not immediately removed, we will sue you for what will doubtless be enormous compensatory and punitive damages.” Nuts! pic.twitter.com/XxxkG43z3W — The Lincoln Project (@ProjectLincoln) October 24, 2020...
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Re: Sensory substitution - 2014년 리뷰 2020.10.24해당카페글 미리보기
be a double-edged sword. On the one hand, it helps the blind to better cope with blindness by supporting compensatory capabilities (Amedi et al., 2003, Amedi et al., 2004, Bedny et al., 2011, Gougoux et al., 2005, Rauschecker, 1995...
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Re: HDACs, histone deacetylation and gene transcription: from molecular bio 2020.10.19해당카페글 미리보기
and their ES cells show decreased growth and enhanced expression of the cyclin-dependent kinase inhibitors p21 and p27 29. Compensatory upregulation of the expression of other class I HDACs in HDAC1 KO cells is apparently insufficient to...
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Re: Food Bioactive HDAC Inhibitors in the Epigenetic Regulation of Heart Fa 2020.10.16해당카페글 미리보기
AMPK levels in the heart [263]. AMPK senses energy needs and stress in the heart. In response to cardiac remodeling, compensatory mechanisms activate AMPK [269]. AMPK activation has been shown to improve cardiac dysfunction [269]. Thus...
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Re: 타우린의 항암효과 - 2020 리뷰논문 2020.10.12해당카페글 미리보기
mine (DEN). The molecular mechanism of DEN is based on triggering irreversible hepatocellular necrosis coupled with compensatory proliferation (107). The DEN-mediated hepatic damage becomes apparent through increased oxidative stress in...
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Being cool: how body temperature influences ageing and longevity 2020.10.11해당카페글 미리보기
to surface ratios and/or in body composition (Bartke 2011); that is, increased oxygen consumption could be a compensatory effect to increased heat loss due to increased body surface:mass ratio in these small animals (Bartke and Westbrook...
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Re:메트포민의 항암 기전 - 2018년 리뷰논문 2020.10.09해당카페글 미리보기
emergence of therapeutic resistance. As a result, sophisticated combinatorial approaches that prevent metabolic compensatory mechanisms will be required to effectively manage metastatic disease. MetforminA Drug With A Long History...
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Re: Impact of proteolytic enzymes in colorectal cancer development and prog 2020.10.09해당카페글 미리보기
seems to reduce invasion and metastasis, but there is concern that selective cathepsin inhibition induces compensatory activity by other cathepsins. The combination of cathepsin inhibition with conventional chemotherapy seems to be more...
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Mitohormesis - 2014 cell membrane 리뷰 2020.10.04해당카페글 미리보기
of metabolism in these animals demonstrated that restricting glucose availability resulted in a presumed compensatory increase in mitochondrial respiration, with evidence for increased utilization of fat through β-oxidation. These...