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Re: 파킨슨 치료 비타민 A, E, D(지용성), B, C(수용성) 2024.07.11해당카페글 미리보기
ROS and RNS [16], and oxidation of dopamine and dopamine metabolites such as 3,4-dihydroxyphenylacetic acid (DOPAC) can inhibit the activity of complex I [17]. These findings indicate that the downstream metabolites of dopamine may make...
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Re: 도파민은 T 세포 면역조절자 역할 ... 논문.. 2024.07.11해당카페글 미리보기
cAMP (Saha et al., 2001a, 2001b). Similarly, stimulation of DA D2 and D3 receptors in T cells has been shown to inhibit activated T cell receptor induced cell proliferation, and secretion of IL-2, IFNγ and IL-4 by down regulating the...
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세포 찌거기 제거. 오토파지.. 운동으로 유도된다... 2024.07.10해당카페글 미리보기
seems to be dependent on the context and subcellular localization, because cytosolic p53 has been shown to inhibit autophagy (Tasdemir et al. 2008), whereas p53 induces transcription of key stimulatory autophagy genes in the nucleus...
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파킨슨 병리 ... jama 논문.. 2024.07.10해당카페글 미리보기
may be inhibited by the accumulation of aggregation-prone proteins,5 including α-synuclein.12 Lewy bodies could inhibit the UPS by saturating and/or sequestering one or more molecular chaperones and/or ubiquitin ligases required for UPS...
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쇼그렌 한약 .. 대만 연구 nature 2024.07.09해당카페글 미리보기
37 and has anti-inflammatory properties38. “Tian-Hua-Fen” can “clear heat and engender liquid,” and it can inhibit nitric oxide activity and elevate anti-inflammatory effects39. “Huang-Qin” can “clear heat and drain fire,” and it...
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Re: 만성염증 자가면역 염증 전환 지점 탐구.. 자가반응 T 세포... 2024.07.08해당카페글 미리보기
to downregulate the ongoing inflammation through increased presence of Tregs, but these are unable to effectively inhibit the disease. As outlined in the introduction, there are at least four mechanisms of rendering Tregs dysfunctional...
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면역세포의 노화. 2023년 nature review 2024.07.06해당카페글 미리보기
T (Treg) cells is increased in the TME,63 and hypoxia-driven accumulation of cyclic adenosine monophosphate can inhibit tumor-specific effector T cells, activating p38 pathways.64,65,66,67 Mechanistically, competition for glucose between...
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만성염증 --> 자가면역으로 전환하는 시점 탐구!! 2024.07.06해당카페글 미리보기
Go to: Why do Tregs fail to suppress during autoimmune disease? Under normal conditions, Tregs effectively inhibit excessive inflammation and autoimmune manifestations [6]. However, in autoimmune diseases Tregs fail to control the...
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Re: 안구건조, 입마름 쇼그렌 증후군 jama 논문 탐구 2024.07.04해당카페글 미리보기
1.5 L of saliva daily. Saliva contains lysozyme, lactoferrin, lactoperoxidase, and histidine-rich polypeptides, which inhibit bacteria and fungi.46,47 Furthermore, salivary glycoproteins are thought to play a role in inhibition of...
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Re: 염증유발 과정에서 NF-κB signaling 탐구 .. 2024.07.04해당카페글 미리보기
p105 and its processing product p50, have also been associated with IBD.98–100 These genetic alterations appear to inhibit NFKB1 gene expression or alter the stability and function of the protein products. Consistently, mice carrying a...