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Re: 면역 조절기능에서 대식세포의 역할 2023년 nature review 2024.07.16해당카페글 미리보기
classical IFN-α macrophage stimulation.21 Again, oxidized lipids in antioxidant macrophages (Mox) are revealed to induce macrophage phenotype.22 In addition, Yi Cai et al. identified a subset of macrophages that are distinguished with...
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Re: 활성산소 --> Cell senescence --> 노화 탐구!! 2024.07.16해당카페글 미리보기
of the regenerative pool of the tissue stem cells [8]. Some observations indicate that senescent cells do not necessarily induce mechanisms that promote aging and can be efficiently removed from the human body [9]. The general consensus...
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Re: 활성산소의 DNA 손상에 대한 탐구!! 2024.07.16해당카페글 미리보기
Reactive oxygen species (ROS) are a group of short-lived, highly reactive, oxygen-containing molecules that can induce DNA damage and affect the DNA damage response (DDR). There is unequivocal pre-clinical and clinical evidence that ROS...
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Re: Re: 활성산소의 지질(lipid) 손상에 대한 탐구!! 2024.07.16해당카페글 미리보기
can generate alkoxyl (RO·) radicals by Fenton chemistry reaction. (b) The products of lipid peroxidation induce apoptosis and autophagy via different pathways. (c) GPX4 activity decreases and a depletion of GSH causes lipid peroxidation...
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Re: Superoxide Anion Chemistry—Its Role at the Core of the Innate Immunity 2024.07.16해당카페글 미리보기
of O2 reduction, necessary for cell signalling, and at the pathological level they are considered harmful, as they can induce disease and apoptosis, necrosis, ferroptosis, pyroptosis and autophagic cell death. This revision focuses on...
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면역반응의 산화, 환원 생리학!! 2022년 nature review 2024.07.15해당카페글 미리보기
result, large increases in the genesis and release of ROS follow [107, 108]. High levels of cytosolic succinate may induce an increase in lysine group succinylation in the cellular proteome, which many influence protein activity via...
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Re: 항산화 치료법으로 질환을 치료하는 관점.. 2021년 nature review 2024.07.15해당카페글 미리보기
perfect system as evidenced by a low rate of oxidized proteins that accumulate with age. Regardless, the ability to induce the enzymes that remove O2•− and H2O2 and damaged proteins in what Davies calls ‘adaptive homeostasis...
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Re: 위장의 염증을 보호하는 산화질소 탐구... 2024.07.15해당카페글 미리보기
and superoxide anion) will all act to elicit downstream effects. The effects of NO reacting with other radicals can induce either deleterious or even beneficial consequences, depending on the conditions under which the process takes...
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Re: 과산화수소(ros, hydrogen peroxide) 지킬박사와 하이드 신호... 2024.07.14해당카페글 미리보기
little is known about the assembly/activation of the other Nox-family members. Cytokines and growth factors induce ROS production through activation of locally recruited Noxs in non-phagocytic cell types.14 Nox1, 2, 3 and 5 produce O2...
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대문 - 근성 2024.07.14해당카페글 미리보기
be very helpful. Also Once you have a grit, you never lose it. And If you think the game is running away, If you induce them to find them to the end, A grit arises. If you try to teach it over and over again, It will be able to instill...