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Re: BCAA 아미노산의 자가포식억제, 비만-당뇨에서 간독성을 유발하는 기전 2020.11.12해당카페글 미리보기
liquid chromatography, HSL, hormone sensitive lipase, IL-1β, interleukin-1β, IL-6, interleukin-6, IP, intraperitoneal injection, IRS1, insulin receptor substrate-1, ISO, isoprenaline, ITT, insulin tolerance test, IU, international unit...
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Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds 2020.11.02해당카페글 미리보기
142 and GSK 897-78c143. In rodents, these molecules have been administered via various routes, including intraperitoneal, gavage and in drinking water, at doses ranging from 100 to 1,000 mg per kg per day67,136–141 for more than 6...
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Re: Citicoline: A Superior Form of Choline? 2020.10.29해당카페글 미리보기
the route administration. Data compiled from refs. [27,28,29,30,31]. Abbreviations used: i.v., intravenous; i.p., intraperitoneal; ND, no data available. The classical measure of acute toxicity is LD50, the median lethal dose of the...
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Neuroprotective Properties of Citicoline: Facts, Doubts and Unresolved Issu 2020.10.29해당카페글 미리보기
the equivalent intravenous dose of the free drug which, in turn, is more neuroprotective than the equivalent intraperitoneal dose. Although other explanations may be speculated upon, the aforementioned result is compatible with the idea...
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Re: 새로운 항암치료 제안 - ONCOLYTIC VIROTHERAPY 2020.10.22해당카페글 미리보기
into solid tumors59 and we recently have shown they could efficiently deliver oncolytic measles viruses to intraperitoneal ovarian cancer deposits in the presence of neutralizing antiviral antibodies60. Cellular carriers should ideally...
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Re:Treatment of Allergic Rhinitis with Probiotics: An Alternative Approach 2020.10.22해당카페글 미리보기
microbial ecosystem and yield a functional or clinical benefit to the host.[28] A recent study showed that intraperitoneal delivery of EcN together with Ovalbumin (OVA)/Alum strongly inhibited the generation of OVA-induced Th2 responses...
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Re: Anticancer mechanisms of cannabinoids 2020.10.22해당카페글 미리보기
or using an oromucosal spray15. Preclinical animal models have yielded data indicating that systemic (oral or intraperitoneal) administration of cannabinoids effectively decreases tumour growth (GV, CS, and MG. Unpublished observations...
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오메가 3 지방산의 항암효과 탐구 - 2020년 논문 2020.10.21해당카페글 미리보기
equal antitumor activity to GEM in various xenograft models. Furthermore, oral administration compared to intraperitoneal administration resulted in equal antitumor activity (Bergman et al., 2011). Tao et al. covalently coupled...
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Modulation of Colitis-associated Colon Tumorigenesis by Baicalein, Betaine 2020.10.13해당카페글 미리보기
an efficient animal model for colitis-related carcinogenesis, male ICR mice were challenged with a single intraperitoneal administration (10 mg/kg body weight) of a genotoxic colonic carcinogen, AOM and an one week oral exposure (2% in...
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Gut microbes and metabolites as modulators of blood-brain barrier integrity 2020.10.12해당카페글 미리보기
of sodium butyrate, by upregulating tight junction proteins.6 Following traumatic brain injury, intravenous or intraperitoneal administration of sodium butyrate can prevent BBB breakdown and promote neurogenesis.30,31,38 It is therefore...