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Re:Re:Efferocytosis at the Interface of Homeostasis and Pathology 2020.09.19해당카페글 미리보기
to lethal anemia in embryos and chronic arthritis in adults (Kawane et al., 2001, Kawane et al., 2006). These observations indicate that dead cells and the nuclei expelled from erythroid precursor cells need to be swiftly cleared for...
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Re: BBB를 통과하는 SAMe 보충제로 치료하는 불면, 불안!! 2020.09.11해당카페글 미리보기
CSF concentration of SAMe in normal infants and youth may be greater than in adults, though rigorous studies of age-related changes in levels of SAMe are needed (139). Trials of SAMe during pregnancy and breast-feeding with long-term...
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Molecular Chaperone Functions in Protein Folding and Proteostasis - 꼭 다시 봐야 2020.09.04해당카페글 미리보기
the concentration of folding intermediates exceeds the available chaperone capacity. Such a situation generally results in the induction of the cellular stress response, which increases the abundance of stress-regulated chaperones. Role...
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Re: Amino Acid Transporters(아미노산 수송체) as Disease Modifiers and Drug Targets 2020.08.25해당카페글 미리보기
the concentration of these allosteric modulators in the synaptic cleft, thereby enhancing NMDA receptor activity. Surprisingly, inhibitors of asc-1 decreased extracellular d-serine levels, suggesting that this transporter is rather...
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Re:Re:Possible role of vitamin D in Covid-19 infection in pediatric population 2020.08.06해당카페글 미리보기
optimal concentration of 25(OH)D and the corresponding dietary requirements or treatment regimen suitable to the given disease. Go to: Vitamin D and pulmonary fibrosis Recently, it has been demonstrated that high levels of vitamin D...
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전쟁터 미국 : 미국 국민들과의 전쟁 2020.07.09해당카페글 미리보기
Former concentration camp inmate Hannah Arendt warned against this when she wrote, “Never has our future been more unpredictable, never have we depended so much on political forces that cannot be trusted to follow the rules of common...
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Re:Re:Re:Re: Critical Role of Zinc as Either an Antioxidant or a Prooxidant in Cellular Systems 2020.07.06해당카페글 미리보기
50% lethal dose for zinc is approximately 3 g/kg body weight, which is over 10-fold higher than that for cadmium and 50-fold higher than that for mercury [43]. There are three major routes of entry by which zinc may reach a toxic level...
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Membrane Repair: Mechanisms and Pathophysiology 2020.07.04해당카페글 미리보기
potentially lethal plasma membrane injuries, including those caused by osmotic stress, by infection from bacterial toxins and parasites, and by mechanical and ischemic stress. The wounded cell can survive if a rapid repair response is...
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Re:Re:세포의 마그네슘 항상성에 관한 논문 2020.06.28해당카페글 미리보기
is lethal to the cell. At the same time, Jiang et al. [80] have reported that 1 hour occlusion of middle cerebral artery enhances TRPM7 expression in ipsilateral hippocampus, with deleterious consequences for the neurons. Pre-treatment...
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세계는 왜 막다른 곳을 향해 치닫나요? 2020.06.26해당카페글 미리보기
were not life-threatening. This contradicts the coroner's own conclusion of homicide. Floyd's blood tests showed a lethal concentration of Fentanyl of about THREE times the maximum that has been recorded in a survivor, even when...