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활성산소.. 적절함 redox biology 과함 oxidative stress.. Redox balance 2024.07.11해당카페글 미리보기
activate transcription factors for adaption to stress [4]. An understood mechanism of redox signaling involves H2O2-mediated oxidation of cysteine residues within proteins [5]. Cysteine residues exist as a thiolate anion (Cys-S-) at...
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Re: 파킨슨 치료 비타민 A, E, D(지용성), B, C(수용성) 2024.07.11해당카페글 미리보기
However, some studies have shown that vitamin E did not completely protect dopaminergic neurons from MPTP-mediated damage in PD models [71, 72]. The protective effects of vitamin E may be achieved through preventing oxidative stress in...
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Re: 도파민은 T 세포 면역조절자 역할 ... 논문.. 2024.07.11해당카페글 미리보기
reports indicate unique interactions between dopamine and T cells, the main focus of this mini-review is on DA mediated regulation of T cell function. 신경 통신에서 신경 전달 물질의 전통적인 역할 외에도 신경 전달 물질이 신경계와 면역계...
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Re: 파킨슨 증상과 진단 ... 논문.. 2024.07.11해당카페글 미리보기
of bradykinesia.28 It is hypothesised that bradykinesia is the result of a disruption in normal motor cortex activity mediated by reduced dopaminergic function. In a study assessing recordings from single cortical neurons in rats with...
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세포 찌거기 제거. 오토파지.. 운동으로 유도된다... 2024.07.10해당카페글 미리보기
protein synthesis or protein breakdown at 2 hours post-exercise (Glynn et al. 2010). This indicates that autophagy-mediated release of amino acids is not involved in anabolic/catabolic processes in the early recovery period. The reported...
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Re: 자가포식-리소좀 시스템 2020 nature 논문 . 2024.07.10해당카페글 미리보기
material to lysosomes via the double-membraned autophagosome. Other forms of autophagy, namely chaperone-mediated autophagy and microautophagy, occur directly on the lysosome. Besides providing the means for degradation, lysosomes are...
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Re: 자가포식-리소좀 시스템 --> 신경퇴행성 . 2024.07.10해당카페글 미리보기
to the lysosome including nonspecific macroautophagy, substrate-specific forms of autophagy (e.g., mitophagy), chaperone-mediated autophagy (CMA), microautophagy, and micropinocytosis, to name a few (Fig. 1). One common feature of all...
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파킨슨 병리 ... jama 논문.. 2024.07.10해당카페글 미리보기
of Lewy bodies.5 Parkin is a ubiquitin E3 ligase that functions to prepare substrates for protein degradation mediated through the ubiquitin-proteasome system (UPS). Initially, much effort was focused on the relationship between parkin...
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Re: 만성염증 자가면역 염증 전환 지점 탐구.. 자가반응 T 세포... 2024.07.08해당카페글 미리보기
layer of the epidermis, the latter being caused by destruction of melanocytes. The hypothesis of it representing a T-cell mediated autoimmune disease is backed up by its HLA association, the identification of melanocyte-derived potential...
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만성염증 자가면역 염증 전환 지점 탐구.. 자가반응 B 세포... 2024.07.08해당카페글 미리보기
Table 1). The presence of autoantibodies, and their described contribution to the pathogenesis of these B cell-mediated autoimmune diseases, is proof of B cell dependency. However, the most conclusive evidence that B cells act as key...