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Re:Re:Calcium, ATP, and ROS: a mitochondrial love-hate triangle 2020.06.12해당카페글 미리보기
with metabolic rate (148, 184), suggesting that a faster metabolism simply results in more respiratory chain electron leakage. In addition, Ca2+ stimulation of nitric oxide synthase (NOS) (3) generates NO·, which inhibits complex IV (34...
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Re:Mitochondrial Retrograde Signaling: Triggers, Pathways, and Outcomes 2020.06.07해당카페글 미리보기
Lactic Acidosis and Stroke-like Episodes) [87], and neurons and glia of the occipital lobe of patients with Alzheimer's disease [88]. While it is clear that stress conditions lead to increments in humanin levels, very little is known...
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Re:Mitochondrial diseases 2020.06.07해당카페글 미리보기
Lactic acidosis (a buildup of lactate). Dementia. How are mitochondrial diseases diagnosed? Because mitochondrial diseases affect so many different organs and tissues of the body, and patients have so many different symptoms...
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대사성산증 2020.06.02해당카페글 미리보기
위 환자를 보면 이산화탄소분압이 28이지 않습니까? 결국 위 환자는 호흡보상이 잘 이루어진 대사성 normal anion gap metabolic acidosis 환자라는 것입니다. anion gap 은 솔직히 저희 임상에서는 크게 알 필요는 없습니다. 단지 공부를 위한 공부일뿐...
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Hyperkalemia 2020.06.02해당카페글 미리보기
glucose K 이온의 세포내로의 이동 촉진 50DW 50ml + RI 10nuit IV Bicarbonate K 이온의 세포내로의 이동 촉진 metabolic acidosis시 NaHco3 3A IV Albuterol K 이온의 세포내로의 이동 촉진 10~20mg nebulizer 2) 급성기 치료 (초치료만 하면 K이온 ECF...
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Re:Re:Protein Degradation by the Ubiquitin–Proteasome Pathway in Normal and Disease States 2020.05.28해당카페글 미리보기
is associated with several physiologic complications that can trigger the UPP to breakdown muscle protein, metabolic acidosis, decreased insulin action, increased glucocorticoids, high levels of angiotensin II, and inflammation (66,71,93...
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Re:Transcription, Processing, and Decay of Mitochondrial RNA in Health and Disease 2020.05.28해당카페글 미리보기
lactic acidosis, and stroke-like episode)-like syndrome [130]. FASTKD2 has been also implicated as a target for modulating neurodegeneration and memory loss in ageing and dementia [118]. Furthermore, FASTKD2 has been also shown to...
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Re:The role of oxidants and free radicals in reperfusion injury 2020.05.19해당카페글 미리보기
intracellular acidosis and severe hypoxia leading to a highly reduced state that subsequently leads to nitrite reduction. To determine if nitrite, NO2−, was reduced during ischemia to form NO, experiments were performed in hearts...
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Fluid는 왜 주는걸까? (crtstalloid/ colloid/ 그외 수액) 2020.05.18해당카페글 미리보기
hypovolemic, sepsis, hemorrhage, GI fluid loss 등에 사용합니다. 다량투여시 Cl이 많아 혈액 내 HCO3가 저하되어 metabolic acidosis, Kidney injury 위험이 있습니다. 과량투여시 수분과다, 고나트륨혈증에 주의해야 합니다. - 3% saline : severe...
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Re:Re:The Role of Thiamine in Cancer: Possible Genetic and Cellular Signaling Mechanisms 2020.05.12해당카페글 미리보기
The metabolic syndrome has been reported to be associated with the risk of prostate cancer in Italian populations (117). Type 1 DM is associated with an increase in the risk of cancer, particularly gastric, uterine cervix, endometrial...