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Membrane Repair: Mechanisms and Pathophysiology 2020.07.04해당카페글 미리보기
vivo infection of C. elegans were shown to occur independently of extracellular calcium in the medium (164). In contrast, removal of large calcium-conductive SLO pores in mammalian cells occurs by rapid calcium-dependent endocytosis (123...
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Re:Re: HEAT SHOCK PROTEINS IN DIABETES AND WOUND HEALING 2020.06.24해당카페글 미리보기
2 (yeast) Ahsa2 Aka: 1110064P04Rik. human ortholog name: HSPB (heat shock 27kDa) associated protein 1 Hspbap1 Aka: 3830421G21Rik. Protein domains: Protein Associated with Small Stress protein 1 (PASS1); Transcription factor jumonji...
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Re:Mitochondrial Retrograde Signaling: Triggers, Pathways, and Outcomes 2020.06.07해당카페글 미리보기
in yeast was reported to extend replicative lifespan [55, 98–100]. The mechanisms are not entirely clear but seem to involve RAS2 [99] as well as a counteraction of negative effects that rise from the age-induced increase in the...
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Re:Re:Caspase involvement in autophagy 2020.06.05해당카페글 미리보기
pathogen-infection.97 The group concluded that even though the exact mechanism warrants further investigation, compromised cytoprotective autophagy in this context appears to be associated with increased bacterial load, further...
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암의원인? - 칸디다균? 2020.06.02해당카페글 미리보기
Candida yeast)는 “단일의 공동 성분(one shared element)”이 아니라, 말하자면, 오히려 “군생적 성분들(social elements)”로서 대단히 밀접한 관계다. 그들의 유일무이한 적응 능력 때문에, 중조(Sodium Bicarbonate)는 직접 종양에 공급되어야 한다...
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Re:Re:Mitochondria: The calcium connection 2020.05.28해당카페글 미리보기
viral infection was stable over time and repeated experiments could be performed through a cranial window several weeks after the initial injection of the viral vector [61], [62], [63]. As pointed out previously, GECIs (and therefore...
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Re:Re:Protein Degradation by the Ubiquitin–Proteasome Pathway in Normal and Disease States 2020.05.28해당카페글 미리보기
bacterial infection or with cancer allows the immune system to screen for non-native proteins within cells (2,53,54). Although the great majority of peptides that are generated by the proteasome during breakdown of intracellular proteins...
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Re:Re:Autophagy: A lysosomal degradation pathway with a central role in health and disease 2020.05.28해당카페글 미리보기
viral infection. Depending on the delivery route of the cytoplasmic material to the lysosomal lumen, three different autophagic routes are known: 1) macroautophagy, or simply autophagy, 2) microautophagy, and 3) chaperone-mediated...
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Re:Principles of lysosomal membrane degradation: Cellular topology and biochemistry of lysosomal lipid degradation 2020.05.28해당카페글 미리보기
In yeast, after fusion with the vacuole, the autophagosome is released into the lumen as a single-membrane vesicle and termed autophagic body. The breakdown of this subvacuolar vesicle depends on the acidic pH of the vacuole [12], and on...
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Re: 아스퍼길루스 (곰팡이균)의 종류와 이해 2020.05.18해당카페글 미리보기
causing infection. Aspergillus is the most morphologically identified in the laboratory. Recently, molecular genetic methods have been proposed for identification of fungi that unidentified morphologically or identified genus level. Of...