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주로 지질, 단백질, DNA를 파괴하는 활성산소 탐구!! 2024.07.03해당카페글 미리보기
diet-derived lipids in the arterial wall and serum to yield peroxides and other substances. These compounds induce endothelial cell injury and produce changes in the arterial walls.[10] 자유 라디칼 반응은 나이가 들면서 신체 전반에 걸쳐...
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Re: 통풍, 요산을 대신하는 항산화제!! 2024.07.02해당카페글 미리보기
and subsequent oxidative cell damage leading to apoptosis. Moreover, hyperuricemia-mediated OS activated RAAS to induce further endothelial damage and was successfully abrogated by probenecid, a urate-lowering agent that blocks entry of...
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Re: B 세포 교차반응 자가면역 질환들 RA, SLE, MS, 당뇨... 2024.06.30해당카페글 미리보기
and denatured collagen [86]. These findings are supported by studies describing that EBV infections in mice may induce erosive arthritis, and the presence of T cell responses in the joints of patients with RA [160,161,162,163]. Another...
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Re: T 세포 교차반응성의 명암... 2024.06.30해당카페글 미리보기
peptides, expression of these allelic products alone is insufficient to cause disease. Other risk factors which may induce increased expression and activity of TG2 may also be involved. For instance, in vivo and in vitro studies support...
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음식 이상반응에서 알레르기 교차반응 epitope 탐구!! 2024.06.30해당카페글 미리보기
among closely related allergen sources.13 A cross-reactive T-cell epitope is able to stimulate memory T cells and induce subsequent IgE production (Fig 2). A well-known example is the Bet v 1 immunodominant T-cell epitope Bet v 1142-156...
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Re: 생선 알레르기의 90% 원인 '파발부민' 탐구 2024.06.30해당카페글 미리보기
sensitive to an allergic reaction. Peanuts, soy, milk, shellfish, fish, and tree nuts are some common foods that induce allergic reactions [42]. These food sources contain high levels of allergens, which remain stable when processed and...
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Re: B 세포 senescence 2024.06.28해당카페글 미리보기
as myeloid DCs (mDCs) or plasmacytoid DCs (pDCs), have distinct functional activities: mDCs produce IL-12 and induce helper T cell type 1 (Th1) and cytotoxic T lymphocyte (CTL) responses, whereas pDCs produce IFN-α/β in response to...
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Re: B 세포와 자가면역 2024.06.28해당카페글 미리보기
promote release of proinflammatory cytokines and serve as chemoattractants for effector cells. Moreover they induce the upregulation of activating FcR on effector cells. Binding of the Fc portion of the antibodies to FcR leads to...
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Re: B 세포 매개 자가면역 2024.06.28해당카페글 미리보기
structure of the antigen, NBCs may or may not need additional help from T cells to fully respond to the antigen. To induce this help, B cells that have been activated by particular protein antigens form cognate interactions with T cells...
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Re: T 세포 매개 자가면역 2024.06.28해당카페글 미리보기
Th2 and Th9, TGF-β for Th9 and Th17, IL-6 for Th17 and Tfh, and IL-2 for Tfh and Treg cells. The same cytokines may induce different downstream signaling cascade and differentiation fate. For instance, IL-6-induced STAT3 activation...