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Re: 만성염증 자가면역 염증 전환 지점 탐구.. 자가반응 T 세포... 2024.07.08해당카페글 미리보기
layer of the epidermis, the latter being caused by destruction of melanocytes. The hypothesis of it representing a T-cell mediated autoimmune disease is backed up by its HLA association, the identification of melanocyte-derived potential...
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만성염증 자가면역 염증 전환 지점 탐구.. 자가반응 B 세포... 2024.07.08해당카페글 미리보기
Table 1). The presence of autoantibodies, and their described contribution to the pathogenesis of these B cell-mediated autoimmune diseases, is proof of B cell dependency. However, the most conclusive evidence that B cells act as key...
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면역세포의 노화. 2023년 nature review 2024.07.06해당카페글 미리보기
age due to thymic degeneration, abnormal T-cell metabolism, changes in the proportion of T subpopulations, and an SASP-mediated chronic low-grade inflammatory environment. IFN-γ interferon-γ, IL-6 interleukin-6, IL-8 interleukin-8, IL...
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Re: T 세포로 보는 자가면역으로 전환하는 시점 탐구!! 2023년 Nature 2024.07.06해당카페글 미리보기
TCR signals in intermediate thymocytes trigger differentiation into CD4+CD8- SP cells largely by inhibiting IL-7-mediated signaling, whereas transient and weak TCR signals force these cells into CD4-CD8+ SP cells, which relies on signals...
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만성염증 --> 자가면역으로 전환하는 시점 탐구!! 2024.07.06해당카페글 미리보기
Treg function, (ii) the issue of Treg plasticity, (iii) the possible resistance of autoimmune T cells to Treg-mediated control, and (iv) Treg-associated inhibitory cytokines TGFβ, IL-10 and IL-35 in facilitating Treg suppressive...
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스트레스 반응이 어떻게 자가면역 쇼그렌증후군을 일으키는가? 2024.07.05해당카페글 미리보기
epithelial cells The salivary gland function is inherent with an ANS function. The stimulation of saliva production is mediated through taste and mastication and depends largely on the ANS. The protein secretion is exclusively controlled...
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Re: 쇼그렌 증후군 최신약물 탐구 노력의 실패!! 2024.07.05해당카페글 미리보기
ROS). Studies also provided evidence of SS pathogenesis via Nod-like receptor family protein 3 (NLRP3) inflammasome-mediated pyroptosis in exocrine glands [Citation29]. Massive circulating cell-free DNA (cf-DNA) accumulation activates...
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누구에게나 쉽게 설명하고 누구나 쉽게 치료할 수 있는 통증 맵 2024.07.04해당카페글 미리보기
trauma to collagen fibres and lasts for 3-5 days, depending on the severity of the injury. The repair phase is mediated by blood clotting over the damaged tissue. Blood platelets form a mesh to initiate healing. Also present in the blood...
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누구에게나 쉽게 설명하고 누구나 쉽게 치료할 수 있는 통증 맵 2024.07.04해당카페글 미리보기
trauma to collagen fibres and lasts for 3-5 days, depending on the severity of the injury. The repair phase is mediated by blood clotting over the damaged tissue. Blood platelets form a mesh to initiate healing. Also present in the blood...
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만성염증 --> 자가면역 염증으로 진행하는 과정의 중요 인자 NF-κB 탐구!! 2024.07.04해당카페글 미리보기
of NF-κB dimers including p65:p50 dimers. In the non-canonical pathway, NEMO-independent activation of IKKα is mediated by the upstream kinase NIK. IKKα, with NIK, induces phosphorylation and processing of p100 to p52 resulting in the...