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Re: The Effects of Dietary Interventions on Brain Aging and Neurological Di 2023.08.09해당카페글 미리보기
such as cognitive and motor-coordination decline, in the normal aging brain through an increase in neurogenesis and synaptic plasticity, and decrease in neuroinflammation, mitochondrial dysfunction, and oxidative stress. We summarize the...
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간헐적 단식 - 치매, 파킨슨, 루게릭 병 치유 기전 2023.08.09해당카페글 미리보기
are linked to the pathological processes of microglia activation, neurotoxic protein accumulation, axonal and synaptic dysfunction, and neuronal death observed in neurodegeneration (Aldana, 2019; Tups et al., 2017; Zilberter and...
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치매 - 인지향상 프로그램 2021년 review논문 2023.08.03해당카페글 미리보기
the induction of a modulation of the neural activity. The basic mechanism is the enhancement or inhibition of synaptic transmission, which can lead to changes in activity in specific cortical areas, and changes in functional connectivity...
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Re: 치매의 원인들 2-3. 인슐린 저항성 --> 치매 2023.08.02해당카페글 미리보기
of the BBB, changing its permeability. This impairment causes cerebrovascular dysfunction, resulting in deficits in synaptic plasticity and cognition. 인슐린 저항성은 BBB를 파괴하여 투과성을 변화시킬 수 있습니다. 이러한 장애는 뇌혈관...
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Re: 치매의 원인들 2-2. 테스토스테론이 낮을수록 치매 위험도 증가 2023.08.01해당카페글 미리보기
to oxidative brain damage in mice [47]. Testosterone and androgen receptor signalling have also been implicated in synaptic formation and plasticity, in the pre-frontal cortex and other areas [48, 49]. However, a study of middle-aged...
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Re: 치매의 원인들 2-1. 폐경이 늦을수록, 에스트로겐 수치가 유지될 수록 치매 위험도는 낮아 2023.08.01해당카페글 미리보기
regulating intracellular Ca2+homeostasis and regulating the function of l-type calcium channel, thereby relating to synaptic function and pathological changes of the AD. 66 In addition, elevated estrogen levels can induce the production...
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Re: 치매의 원인들 2-2. 비타민 e 부족(Vitamin e deficiency) 2023.07.30해당카페글 미리보기
functioning. Indeed, even if its role is not completely clear, it is involved in brain development, memory and synaptic plasticity. Three isoforms of APP exist, namely APP695, APP751 and APP770, which are generated by alternative...
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Re: 치매의 원인들 1-1. 철분, 셀레늄, 칼슘 부족증, 칼륨, 마그네슘 과잉 2023.07.30해당카페글 미리보기
and the effects of the endoplasmic reticulum (ER)-resident protein SELENOK on Ca2+ homeostasis and receptor-mediated synaptic functions. This review discusses selenoproteins that are closely associated with brain function and the...
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치매의 원인들 1. 아연 부족(zinc deficiency) 2023.07.30해당카페글 미리보기
of free zinc or non-compactly bound zinc. In addition, it is mostly stored in the vesicles of excitatory glutamatergic synaptic neurons and is released into the synaptic gap along with glutamate upon stimulation of neurons [8]. Due to...
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에델만의 1차 의식과 고차 의식:기억된 현재와 언어에 물든 세컨드 네이처(제2의 자연, 가상세계) 2023.07.27해당카페글 미리보기
신경연결이다. 동물의 정신현상들, 예컨대 기억, 의식, 감정 등은 시냅스의 시간에 따른 통계적 변화로 나타난다. 시냅스의 강도synaptic strength에 따라 신경세포들의 이런 다중 연결로 우리는 외부 세계를 인식하고, 내부의 욕구에 적응하며 감각 입력...