카페검색 본문
카페글 본문
-
고주파온열암(42도)의 항암효과 2020.02.10해당카페글 미리보기
ATP concentration. The major consequence of the low ATP is the inhibition the ATP dependent enzyme activity. 3.5. Effects on Heat Shock Proteins and the Consequent Immunomodulation Protein damage is the main molecular event underlying...
-
Re:Re:Application of Berberine on Treating Type 2 Diabetes Mellitus 2020.02.08해당카페글 미리보기
oral lethal dose of the total extract of RC was 2.95 g/kg in mice. The toxic constituents of RC were the alkaloids, mainly BBR. Generally, BBR in combination with other natural plants shows very less toxicity and side effects [20]. Kheir...
-
Re:Re:Ketogenic Diet and Skeletal Muscle Hypertrophy: A Frenemy Relationship? 2020.02.08해당카페글 미리보기
increased concentration of AA, insulin or subsequent to mechanical stress induced by muscle contraction, mTORC1 complex translocates into the lysosome where it can interact with the G-protein Ras homolog enriched in the brain (Rheb) (Bar...
-
Re:Re: Reactive Oxygen Species in Metabolic and Inflammatory Signaling 2020.02.06해당카페글 미리보기
NADPH concentration as a by-product of increased glycolysis is hypothesized to further enhance NOX2 activity; however, this has yet to be proven.8 In addition to NOX-dependent ROS production, the nitric oxide synthases (eNOS [endothelial...
-
Re:Re:Doxycycline Vitamin C Anti Cancer Synergy 2020.02.05해당카페글 미리보기
a concentration of only 10 nM, effectively inhibited OXPHOS and ultimately ATP production, by more than 90% overall. As a consequence, DPI treatment induced a reactive glycolytic phenotype, resulting in the production of high levels of L...
-
Re:Re:글루타치온의 항암효과 기전 2019년 REVIEW 2020.02.03해당카페글 미리보기
GSH concentration in the nucleus, studies have confirmed the important role of nuclear GSH in the cell cycle [16, 34, 35]. Cells that are ready for division have higher levels of nuclear GSH [13, 36]. Although there is no definitive...
-
Re:Re: Metabolic Reprogramming of Cancer Associated Fibroblasts: The Slavery of Stromal Fibroblasts 2020.02.01해당카페글 미리보기
O2 concentration but also under normoxic conditions. HIF-1α stabilization is brought about by a loss of Cav-1, leading to an induction of oxidative stress in CAFs creating a pseudo-hypoxic state [67]. A proteomic analysis of Cav-1...
-
Re:Vitamin A, Cancer Treatment and Prevention: The New Role of Cellular Retinol Binding Proteins 2020.02.01해당카페글 미리보기
the concentration of present retinoic acids [5]. Retinoids can activate gene expression by specific nuclear retinoid acid receptors. Two distinct classes of nuclear proteins, the retinoic acid receptors (RARs), and the retinoid X...
-
Re: 아연의 항염증 효과 논문 2020.02.01해당카페글 미리보기
a lethal dose of sodium pentobarbital 24 h later and bronchoalveolar lavage (BAL) fluid was isolated (Figure (Figure1A).1A). These studies were approved by the Cincinnati Children's Hospital Medical Center Institutional Animal Care and...
-
Re: 비타민 D의 항암효과 Nature 논문 2020.02.01해당카페글 미리보기
of lethal prostate cancer progression and cancer death112 and also nuclear VDR expression is associated with better overall survival in lung cancer patients113. Consistently, a recent study showed that reduced VDR protein expression is...