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Re:아토피 행진(알레르기 행진) The Atopic March: Critical Evidence and Clinical Relevance 2020.04.06해당카페글 미리보기
distant tissue sites.41–43 Together, these observations offer one immunologic mechanism by which the presence of a TH2 response to one allergen could potentiate the development of additional TH2 responses. Clinical strategies aimed at...
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Re:Re: AMP-activated Protein Kinase (AMPK): Does This Master Regulator of Cellular Energy State Distinguish Insulin Sensitive from Insulin Resistant O 2020.04.06해당카페글 미리보기
and subcutaneous) than their insulin resistant counterparts [4•, 5, 6]. In addition, they are less likely to develop atherosclerotic cardiovascular disease [7••], and presumably other obesity-associated comorbidities although the...
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Re:Re:Re:Taurine and its analogs in neurological disorders: Focus on therapeutic potential and molecular mechanisms - 2019 리뷰논문 2020.03.23해당카페글 미리보기
99]. Subcutaneous administration of taurine (5 g/kg) protects against ethanol-mediated apoptosis in cells in the cerebellum. Taurine treatment prevents caspase-3 activation and DNA fragmentation via resorting Bcl-2, regulating [Ca2+]i...
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Re:Re:Re:Mechanism of taurine-induced apoptosis in human colon cancer cells 2020.03.23해당카페글 미리보기
in subcutaneous tumor models Four-week-old female nude mice (four in each group) were subcutaneously injected with 0.2 ml of LoVo and HT-29 cells (5.0 × 107 cells/ml) in the right and left flanks. Nude mice were treated every 48 h for...
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Re:Re:Re:Can Ketones Help Rescue Brain Fuel Supply in Later Life? Implications for Cognitive Health during Aging and the Treatment of Alzheimer’s 2020.03.23해당카페글 미리보기
have virtually no adipose tissue so they have very limited ability to store MCFA and, hence, poor ability to generate...weaning (Robinson and Williamson, 1980). Human babies on the other hand have significant subcutaneous fat stores, i.e...
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Re:Re:Re: Perturbed Energy Metabolism and Neuronal Circuit Dysfunction in Cognitive Impairment 2020.03.22해당카페글 미리보기
brain tissue samples from AD patients,83 and experimental findings in animal models of aging and AD suggest that mitochondrial dysfunction is both necessary and sufficient for impaired cognitive function.7,8 Mitochondria are located in...
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혈액순환계와 림프순환계에 관하여 비교정리 2020.03.19해당카페글 미리보기
림프계(subcutaneous LS), 근막상 림프계(suprafacial LS), 근막위림프계(epifascial LS)라 고도 한다 심부림프계(deep lymphatic system): 근막하 림프계(subfascial LS)라고도 한다. 근막아래 피부를 제외한 모든근육, 건, 인대, 뼈, 골막 등에 존재하는...
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Re:Re: Direct Activation of Bax Protein for Cancer Therapy 2020.03.13해당카페글 미리보기
bearing subcutaneous lung cancer xenograft derived from A549 cells. Significant antitumor efficacy was observed at the doses of 40 mg/kg and 60 mg/kg with treatment for 14 days. Body weight change of mice was monitored once every other...
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Mucosal Immunology of Food Allergy 2020.02.21해당카페글 미리보기
the subcutaneous route induces protective mucosal immunity [72]. Like retinoic acid, vitamin D can influence T- and B-cell homing, and has been shown to suppress the development of Th17 cells in vivo [73]. Vitamin D deficiency also...
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Re:Glutamine and cancer: cell biology, physiology, and clinical opportunities 2020.02.17해당카페글 미리보기
amplified subcutaneous and transgenic tumors in mice. The PKC isoform PKC-ζ also regulates glutamine metabolism. Loss of PKC-ζ enhances glutamine utilization and enables cells to survive glucose deprivation (32). This effect requires...