카페검색 본문
카페글 본문
-
Re: Reprogramming the Epigenome With Vitamin C 2022.10.09해당카페글 미리보기
16 July 2019 Sec. Stem Cell Research https://doi.org/10.3389/fcell.2019.00128 This article is part of the Research Topic Epigenetic Regulation of Stem Cell Plasticity in Tissue Regeneration and Disease View all 5 Articles Reprogramming...
-
Re: 텔로미어, 노화, genomic instability, vitamin C 그림 이해 2022.10.09해당카페글 미리보기
29 July 2020 / Accepted: 30 July 2020 / Published: 6 August 2020 https://cafe.daum.net/panicbird/S5zw/195 Re:Epigenetic Regulation of Genomic Stability by Vitamin C REVIEW articleFront. Genet., 04 May 2021Sec. Nutrigenomicshttps://doi...
-
Re:Epigenetic Regulation of Genomic Stability by Vitamin C 2022.10.09해당카페글 미리보기
REVIEW article Front. Genet., 04 May 2021 Sec. Nutrigenomics https://doi.org/10.3389/fgene.2021.675780 Epigenetic Regulation of Genomic Stability by Vitamin C DNA methylation plays an important role in the maintenance of genomic...
-
Re: Targeting the molecular & cellular pillars of human aging with exercise 2022.10.08해당카페글 미리보기
including macromolecular damage, dysregulated stress response, disruption in proteostasis, metabolic regulation, epigenetic drift, inflammaging, and stem-cell exhaustion (Fig. 1) [[17]]. Scientists can rely on these conserved drivers of...
-
Age-related alterations and senescence of mesenchymal stromal cells 2022.10.08해당카페글 미리보기
telomere shortening, accumulation of oxidative damage, impaired DNA repair, altered gene expression profiles, and epigenetic alterations (Marie, 2014; Meng et al., 2020; Yu et al., 2018). Extrinsic aging mechanisms are related to changes...
-
7 Pillars OF Aging 2014년 2022.10.08해당카페글 미리보기
studies Epigenetics Biomarker development: chronologic vs. biologic aging Link age-related environmental inputs to epigenetic signatures Test small molecules that regulate enzymes controlling epigenetic events Inflammation Differentiate...
-
Re: Understanding muscle regenerative decline with aging 2022.10.07해당카페글 미리보기
alterations in ECM signaling to impair satellite cell function. Intrinsic changes to the satellite cell include epigenetic changes and defects in autophagy, leading to increased senescence and apoptosis. These changes manifest in...
-
Re: Targeting Mitochondrial Biogenesis with Polyphenol Compounds 2022.10.07해당카페글 미리보기
DNA structure that ultimately activates transcription. Besides, phosphorylation of DNA methyltransferase 1 as an epigenetic factor, aka DNMT1 by AMPK, restricts the access of transcription factors to promoters. [27]. Figure 1 represents...
-
Cellular Senescence in Brain Aging 2022.10.07해당카페글 미리보기
accumulation of lipid droplets, increased activity of senescence-associated-β-galactosidase (SA-β-gal), and epigenetic alterations, including DNA methylation, chromatin remodeling, and histone post-translational modifications that, in...
-
senolytics, 세포 노화의 처리 2022.10.03해당카페글 미리보기
repair and regeneration [25,26], where it can promote the clearance of cell debris, reduces fibrosis, elicits epigenetic alterations and acts as a potent barrier against tumorigenesis, while also leading to senescence spread, DNA damage...