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Re:The Role of Mitochondria in Apoptosis 2020.01.29해당카페글 미리보기
embryonic lethal owing to Cyt c’s indispensable role in mitochondria electron transport chain. Nonetheless, cyt c−/−MEFs exhibit resistance to a variety of apoptotic stimuli (82). Later, a knockin mouse model was made with Cyt c K72A...
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Re:캠프페롤의 항암효과(암세포 포도당수용체 억제 등) 2020.01.27해당카페글 미리보기
the concentration of CDK remains constant. However, the introduction of kaempferol has been shown to reduce CDK1 levels in human breast cancer MDA-MB-453 cells (Choi and Ahn, 2008). Consequently, kaempferol was able to inhibit...
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Re:The milk revolution 네이처 논문 2020.01.24해당카페글 미리보기
it's lethal, but it's quite unpleasant.” MAP SOURCE: REF. 2 Expand Most people who retain the ability to digest milk can trace their ancestry to Europe, where the trait seems to be linked to a single nucleotide in which the DNA base...
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Re:Serum ferritin is an important inflammatory disease marker 혈청페리틴은 왜 활성산소(산화스트레스)의 표지자인가? 2020.01.24해당카페글 미리보기
embryo-lethal138 but that heterozygous Fth+/− mice are fairly normal save that they have greatly increased levels of serum ferritin but unchanged serum iron.139 This shows us, importantly, (i) that iron and ferritin can be regulated...
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Re:Role of Hormesis in Life Extension by Caloric Restriction 2020.01.20해당카페글 미리보기
plasma concentration of corticoid-binding globulin (Sabatino et al, 1991). It is the level of the free hormone that underlies the physiological actions of this hormone (Mendel, 1989). This daily elevation of plasma corticosterone...
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암세포의 글루타민 대사에 대하여 2020.01.18해당카페글 미리보기
embryonic lethal in mice at day E2.5. GS-knockout embryos can be grown in vitro by supplementation with glutamine, with no observable growth or morphological defects. Complete deficiency in GS in human patients has not been reported in...
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Re:Re: Iron and cancer: recent insights 2020.01.05해당카페글 미리보기
ferritin concentration and prognosis in carcinoma of the breast. Breast Cancer Res Treat. 1989;14:349–353. [PubMed] [Google Scholar] 25. Marcus DM, Zinberg N. Isolation of ferritin from human mammary and pancreatic carcinomas by means...
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황화수소(hydrogen sulfide)의 항암치료 효과 2020.01.04해당카페글 미리보기
normally lethal hypoxia conditions. The longest exposure to 5% O2 was 6.5 hours and H2S-pretreated mice survived without notable damage. Although these interesting experiments revealed promising effects of H2S gas in reducing mice...
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Re:Molecular hydrogen: a preventive and therapeutic medical gas for various diseases 2020.01.04해당카페글 미리보기
H2 concentration, and length of H2 exposure. A recent study showed that H2 administration without surgery did not exert neuroprotective effects or improve functional outcomes in rats after intracerebral hemorrhage [109]. For spinal cord...
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Re: 비타민 D는 종양생성을 막는 역할!! 2020.01.03해당카페글 미리보기
D concentration and subsequent risk of total and site specific cancers in Japanese population: Large case-cohort study within Japan Public Health Center-based Prospective Study cohort. BMJ. 2018;360:k671. doi: 10.1136/bmj.k671. [PMC free...