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Re: 케토제닉 다이어트로 치료하는 루게릭 병 2020.02.08해당카페글 미리보기
compliance), acidosis, and hypoglycemia (Dhamija et al., 2013; Branco et al., 2016). Long-term side effects include hypercholesterolemia, nephrolithiasis, and premature heart disease (Dhamija et al., 2013). Some authors showed that 15...
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Re:Ketogenic diet in endocrine disorders: Current perspectives 2020.02.08해당카페글 미리보기
disease, failure to thrive, severe gastroesophageal reflux, poor oral intake, cardiomyopathy, and chronic metabolic acidosis) may prevent initiation of KD.[25] Lot of therapeutic medications including many anticonvulsants may have high...
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Re:Metabolism of ketone bodies during exercise and training: physiological basis for exogenous supplementation 2020.02.08해당카페글 미리보기
the metabolic effects specific to KBs has proved challenging. Therefore, exogenous ketone supplementation is a means to address these questions and explore potential for performance and therapeutic benefits. Oral administration of KBs in...
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Re:Re: Branched-Chain Amino Acids (Leucine, Isoleucine, and Valine) and Skeletal Muscle 2020.02.07해당카페글 미리보기
molecules that result from glucose metabolism are converted to lactic acid, the buildup of which can lead to metabolic acidosis with pH levels as low as 6.4.[21] High levels of lactic acid cause glucose metabolism to stop in order to...
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Re:Re: 케톤체의 간질치료 원리 2020.02.06해당카페글 미리보기
cerebral acidosis. Epilepsia. 1996;37:258–261. [PubMed] [Google Scholar] Appleton DB, DeVivo DC. An animal model for the ketogenic diet. Epilepsia. 1974;15:211–227. [PubMed] [Google Scholar] Aronica E, Iyer A, Zurolo E, Gorter JA...
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Re:Re: Impairments in Oxidative Glucose Metabolism in Epilepsy and Metabolic Treatments Thereof 2020.02.06해당카페글 미리보기
lactic acidosis and/or energy deficits. In humans with epilepsy and in several rodent epilepsy models, glucose metabolism is impaired. A deficiency in energy is likely to contribute to the generation of seizures, as the stabilization of...
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Re: 뇌의 탄수화물 수용체 유전자 돌연변이가 발생하여 발생하는 간질 - 케토제닉 다이어트로 치료하는 법 2020.02.06해당카페글 미리보기
of fatty acids), acetazolamide, topiramate, and zonisamide (inhibition of carbonic anhydrase which potentiate metabolic acidosis and kidney stones)—and patients affected with Glut1-DS are advised to avoid barbiturates (especially in...
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Re:Re:케톤체의 암 악액질 감소기전 2020.02.03해당카페글 미리보기
and metabolic alterations in cancer, a ketogenic diet may provide an efficient therapeutic strategy. Furthermore, most cancer cells lack key mitochondrial enzymes to metabolize ketone bodies and generate ATP, while myocytes and other...
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Re:젖산을 에너지원으로 사용하는 암세포, 그리고 치료적 전략 2020.02.01해당카페글 미리보기
epigenetic regulation (81). This promiscuous enzymatic activity of LDHA might represent a metabolic response to multiple environmental stimuli including hypoxia and acidosis, conditions frequently found in tumor microenvironment of...
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케톤혁명 4. 케톤식 효과를 높이는 방법 2020.02.01해당카페글 미리보기
6.5. This acidosis favors processes such as metastasis, angiogenesis and more importantly, immunosuppression, which has...clinical prognosis. Thus, lactate should be thought as an important oncometabolite in the metabolic reprogramming...