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Re: 만성염증의 이해 2022.10.21해당카페글 미리보기
the agent causing an acute inflammation such as infectious organisms including Mycobacterium tuberculosis, protozoa, fungi, and other parasites that can resist host defenses and remain in the tissue for an extended period. Exposure to a...
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Re: The Impact of Dietary Sphingolipids on Intestinal Microbiota and Gastro 2022.10.11해당카페글 미리보기
FAs reducing serum and hepatic lipid concentrations in a dose dependent manner (48, 49). Investigations reported different inhibition patterns of intestinal cholesterol absorption when administering egg or milk SM. A stronger inhibitory...
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Re: Protein clearance strategies for disease intervention 2022.10.09해당카페글 미리보기
Whereas reducing USP14 activity can have beneficial effects in distinct disease models, overexpression of USP14 reduces mutant HTT aggregates and counteracts cell degeneration in neural cell lines expressing expanded-polyQ HTT constructs...
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Re:Epigenetic Regulation of Genomic Stability by Vitamin C 2022.10.09해당카페글 미리보기
anticancer agent (Das et al., 2021), modulator of immune responses (Yue and Rao, 2020), and in the reprogramming of stem cells (Lee Chong et al., 2019), herein we highlight these activities within a context of DNA damage, repair, and...
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Re: Targeting Mitochondrial Biogenesis with Polyphenol Compounds 2022.10.07해당카페글 미리보기
through reducing fission and stimulating fusion. Lately, Sharma et al. [69] investigated that acquiring a daily quercetin regimen for 12 weeks by gavage stimulated the biogenesis of mitochondria in a PGC-1α/NRF-1-NRF-2-TFAM-related...
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Senolytic drugs: from discovery to translation 2022.10.03해당카페글 미리보기
endurance, reducing extent of weight loss, and enhancing lung compliance in a mouse bleomycin inhalation‐induced pulmonary fibrosis model of IPF. Another lung condition that might be alleviated by senolytics is hyperoxia‐induced damage...
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스포츠(여가활동)은 서구의 청소년 사회 문제를 해결하는 데 매우 중요한 역할을 해왔다. 2022.09.30해당카페글 미리보기
goals: reducing school absenteeism and truancy, decreasing the incidence of failing grades, increasing self esteem, self-confidence, and cultural pride (Witt and Crompton, 1996). To set clear and persuasive goals, identifying appropriate...
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Re: 미토콘드리아 숫자 늘리기(biogenesis) 2020년 최신 논문 2022.09.21해당카페글 미리보기
antineoplastic agent; in prostate cancer cells, it stabilizes NRF‐2, increases the expression of PGC‐1α and decreases the level of hypoxia‐inducible factor‐1α (HIF‐1α). 85 Chemotherapy medication with cisplatin stimulates PGC‐1...
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Neuroinflammation: A Potential Risk for Dementia 2022.09.20해당카페글 미리보기
promising agent for the management and treatment of AD, but when investigated for clinical efficacy, the monoclonal antibody solanezumab did not substantially impact cognitive decline [25]. Pharmacological approaches for the symptomatic...
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[FRCP] Hickman v. Taylor 2022.09.01해당카페글 미리보기
thus reducing the possibility of surprise. But discovery, like all matters of procedure, has ultimate and necessary boundaries. As indicated by Rules 30 (b) and (d) and 31 (d), limitations inevitably arise when it can be shown that the...