카페검색 본문
카페글 본문
-
Re: 면역 조절기능에서 대식세포의 역할 2023년 nature review 2024.07.16해당카페글 미리보기
tularensis delivers a surface polysaccharide O-antigen and camouflages itself legitimately, which forestalls cytoplasmic pathogenic detection and outcomes in xenophagy. Then again, cytosolic O-antigen mutants were destroyed inside murine...
-
Re: 활성산소 --> Cell senescence --> 노화 탐구!! 2024.07.16해당카페글 미리보기
a quite normal lifespan. OS effect on worms' lifespan depends on where ROS are produced: high mitochondrial or cytoplasmic levels are associated with increased and decreased lifespan, respectively [109, 112]. It remains to define whether...
-
Re: 활성산소 연구의 히스토리.. 2024.07.16해당카페글 미리보기
lack of an active repair mechanism for oxidized RNA, less protection by proteins than DNA and moreover these cytoplasmic RNAs are located in close proximity to the mitochondria where loads of ROS are produced. Indeed, RNA is subjected to...
-
Re: Superoxide Anion Chemistry—Its Role at the Core of the Innate Immunity 2024.07.16해당카페글 미리보기
POR, and electron transport chains found in the endoplasmic reticulum, peroxisomes, nuclear membrane and cytoplasmic membrane, convert O2 to superoxide [24], Figure 8. Superoxide can also be produced non-enzymatically. Figure 8 Enzymatic...
-
Re: 과산화수소(ros, hydrogen peroxide) 지킬박사와 하이드 신호... 2024.07.14해당카페글 미리보기
the formation of the active Nox complex, coupled with various combinations of protein subunits. These activating cytoplasmic proteins include p22phox, p47phox and homologue NoxO1, p67phox and homologue NoxA1, and Rac1/2.12 Activation of...
-
활성산소.. 적절함 redox biology 과함 oxidative stress.. Redox balance 2024.07.11해당카페글 미리보기
kinase activity of their receptors (RTK) that leads to the phosphorylation of specific tyrosine residues on the cytoplasmic tails of the receptor [17]. This recruits multiple proteins to the receptor resulting in activation of several...
-
Re: 자가포식-리소좀 시스템 2020 nature 논문 . 2024.07.10해당카페글 미리보기
abilities from the lysosome. The most well-studied form of autophagy is macroautophagy, which delivers cytoplasmic material to lysosomes via the double-membraned autophagosome. Other forms of autophagy, namely chaperone-mediated...
-
Re: 자가포식-리소좀 시스템 --> 신경퇴행성 . 2024.07.10해당카페글 미리보기
CLEAR-dependent transcription promotes processes that lead to the isolation from the cytoplasm of unwanted cytoplasmic macromolecules, and their permanent removal via degradation and/or exocytosis (Decressac et al. 2013; Polito et al...
-
파킨슨 병리 ... jama 논문.. 2024.07.10해당카페글 미리보기
pathogenic, it is unclear whether these mutations result in an altered functional protein or enhance the rate of cytoplasmic synuclein aggregation leading to disease. Parkin mutations (PARK2) cause a form of autosomal recessive juvenile...
-
Re: 만성염증 자가면역 염증 전환 지점 탐구.. 자가반응 T 세포... 2024.07.08해당카페글 미리보기
where a CD19-specific CAR, composed of an extracellular single-chain variable fragment antibody fused to cytoplasmic signaling domains, triggers cytotoxic T-cell reactions upon contact with CD19+ B-lymphocytes, which results in specific...