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스트레스 반응이 어떻게 자가면역 쇼그렌증후군을 일으키는가? 2024.07.05해당카페글 미리보기
glands concurrently receive signals from ANS in response to stress. The decrease in parasympathetic tone leads to decreased watery component of saliva, while the increase in catecholamine levels results in an increase in the...
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Re: 쇼그렌 증후군 최신약물 탐구 노력의 실패!! 2024.07.05해당카페글 미리보기
of SS [Citation52]. It was reported that the function of the hypothalamic–pituitary–adrenal (HPA) axis is decreased in SS patients [Citation53], leading to lower basal adrenocorticotropic hormone and cortisol levels, promoting fatigue...
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Re: 안구건조, 입마름 쇼그렌 증후군 jama 논문 탐구 2024.07.04해당카페글 미리보기
even though the eyes' appearance is normal. Ocular complaints may include photosensitivity, erythema, eye fatigue, decreased visual acuity, a discharge in the eyes, and the sensation of a film across the visual field.1,23 Ocular symptoms...
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만성염증 --> 자가면역 염증으로 진행하는 과정의 중요 인자 NF-κB 탐구!! 2024.07.04해당카페글 미리보기
Figure 3). Indeed, deletion of the kinase TAK1, an upstream component of both NF-κB and AP1 pathways, results in decreased antiapoptotic gene expression, hematopoietic stem cell apoptosis, and failure of hemtopoiesis 23. However, in...
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Re: NF-κB 탐구!! NF-κB in biology and targeted therapy 2024 네이처 논문 2024.07.04해당카페글 미리보기
kinase 1 alpha (CK1alpha) complex phosphorylates and inactivates β-catenin. NF-κB transcriptional activation is decreased in GSK3-deficient embryonic fibroblasts without affecting IκB degradation and nuclear translocation of NF-κB...
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Re: 활성산소(산화물질)을 생성하는 기관은? 미토콘드리아, 페록시좀 2024.07.03해당카페글 미리보기
from mice (Peeters et al., 2015), and (iii) the activities of the muscle mitochondrial RCCs II, III, and IV are decreased in a Zellweger syndrome (ZS) patient with homozygous pathogenic mutations in the PEX16 gene (ZS is the most severe...
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Re: 췌장암.. 어떻게 발병하고, 어떻게 진단하고 치료하는가? 최신논문.. 2024.07.02해당카페글 미리보기
distinct roles in pancreatic tumorigenesis.69,70 One recent study showed that inhibition of Hedgehog signaling decreased the proportion of myofibroblastic CAFs and altered the immune cell composition, suggesting intricate crosstalk...
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Re: 통풍, 요산을 대신하는 항산화제!! 2024.07.02해당카페글 미리보기
of intrarenal inflammation and OS markers [9]. In rats, chemically-induced hyperuricemia was associated with decreased renal function mainly due to enhanced OS, systemic and glomerular hypertension, glomerular hypertrophy, and vascular...
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NVC_7월 2일(화) 2장. Communication that blocks Compassion 2024.07.02해당카페글 미리보기
of either external or internal coercion. They, too, pay emotionally, for they are likely to feel resentment and decreased self-esteem when they respond to us out of fear, guilt, or shame. 또는 혹시 그 사람들이 우리의 가치관들에 대해 동의...
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Re: B 세포 교차반응 자가면역 질환들 RA, SLE, MS, 당뇨... 2024.06.30해당카페글 미리보기
role, as some patients with autoimmune diseases have a lower cancer risk [64]. Moreover, it has been noted that decreased levels of self-reactive antibodies may correlate with increased susceptibility to the development of autoimmunity...