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Crosstalk of reactive oxygen species and NF-κB signaling 2024.07.04해당카페글 미리보기
which may also utilize other pathways to produce ROS for use in their signaling pathways. Lastly, metabolic enzymes often create ROS as side products or through nonspecific reactions. Full size image In the first category, the...
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Re: NF-κB 탐구!! NF-κB in biology and targeted therapy 2024 네이처 논문 2024.07.04해당카페글 미리보기
transduction from the cell surface to the nucleus through phosphorylation events. This pathway involves three key enzymes: mitogen-activated protein kinase kinase kinase (MAPKKK), mitogen-activated protein kinase kinase (MAPKK), and...
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Re: 활성산소(산화물질)을 생성하는 기관은? 미토콘드리아, 페록시좀 2024.07.03해당카페글 미리보기
here it is worthwhile to mention that the mitochondrial inner membrane contains at least three NO•-producing enzymes: a posttranslationally modified splice variant of neuronal NOS (NOS1α), called mitochondrial NOS (mtNOS) (Ghafourifar...
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주로 지질, 단백질, DNA를 파괴하는 활성산소 탐구!! 2024.07.03해당카페글 미리보기
heat injury, hypertoxia, toxins, and excessive exercise. These injured tissues produce increased radical generating enzymes (e.g., xanthine oxidase, lipogenase, cyclooxygenase) activation of phagocytes, release of free iron, copper ions...
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Re: 췌장암.. 어떻게 발병하고, 어떻게 진단하고 치료하는가? 최신논문.. 2024.07.02해당카페글 미리보기
to clustered nucleotide substitutions, in PDAC; this process is likely associated with the activity of APOBEC enzymes.29 PDAC는 적어도 부분적으로는 발암 유전자와 종양 억제 유전자의 체세포 돌연변이에 의해 발생합니다(그림 2). PDAC에서 가장...
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췌장암..췌장 소화효소 항암효과 최신 논문.. 2024.07.02해당카페글 미리보기
com/watch?v=7wV1sdOIY20 Open access Review article First published online May 5, 2022 Pancreatic Proteolytic Enzymes and Cancer: New Support for an Old Theory Linda L. Isaacs, MD https://orcid.org/XXXX-XXXX-XXXX-XXXX lindaisaacsmd...
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음식 이상반응에서 알레르기 교차반응 epitope 탐구!! 2024.06.30해당카페글 미리보기
specific IgE antibodies preferentially recognize sequential epitopes. However, CN is easily degraded by digestive enzymes such as pepsin and trypsin, so major IgE-binding epitopes exist at amino acid sequence sites that are not cleaved...
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우유 과민증의 원인 'A1 베타-카제인(BCM-7)' 과 유당... 2024.06.30해당카페글 미리보기
some European herds some 5000–10,000 years ago [4]. Once milk or milk products are consumed, the action of digestive enzymes in the gut on A1 beta-casein releases the bioactive opioid peptide BCM-7 [5,6,7,8,9]. In contrast, A2 beta...
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Re: B 세포와 자가면역 2024.06.28해당카페글 미리보기
to FcR leads to activation of effector cells and further release of proinflammatory cytokines and proteolytic enzymes, mediators of antibody-dependent cell-mediated cytotoxicity (ADCC). (c) Effect of antibodies and antigen-specific B...
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밀, 보리(글루텐) 만성염증, 자가면역 염증 과정 최신 논문... 2024.06.26해당카페글 미리보기
are complex proteins unusually rich in prolines and glutamines and are not completely digestible by intestinal enzymes [24]. The final product of this partial digestion is a mix of peptides that can trigger host responses (increased gut...