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Re: 성상교세포의 활성.. 파킨슨 병 역할 탐구... 2024.07.24해당카페글 미리보기
animals; mouse neurons N = 2 animals. Abbreviation: FPKM, fragments per kilobase of transcript per million mapped reads. Graph shows mean ± SD. Data obtained from Supplementary Table S4 in the original publication [11], and can be...
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음식치료제 : 베타 하이드로뷰티레이트(케톤체) 탐구!! 2024.07.17해당카페글 미리보기
of macrophages via the production of PGD2 by COX1 (103). The neuroprotective effect of ketogenic diet in a mouse stroke model is abrogated in Hcar2 knockout mice, and it appears that activation of HCAR2 on brain-infiltrating macrophages...
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활성산소.. 적절함 redox biology 과함 oxidative stress.. Redox balance 2024.07.11해당카페글 미리보기
SOD1 knockout mice. Accordingly, both the type of ROS and it's local concentration collectively determine whether redox signaling or oxidative stress induced damage occurs. In this review we will discuss the two faces of ROS biology...
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Re: 파킨슨 치료 비타민 A, E, D(지용성), B, C(수용성) 2024.07.11해당카페글 미리보기
a mouse model of PD. Meanwhile, they found δ-tocotrienol administration can reduce the loss of dopaminergic neurons in the substantia nigra and ER inhibitors can attenuate this neuroprotective effect [75]. These findings indicate...
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세포 찌거기 제거. 오토파지.. 운동으로 유도된다... 2024.07.10해당카페글 미리보기
He et al. 2012). On the other hand, inducible muscle-specific knockout (KO) of ATG7 resulted in impaired exercise-induced autophagy, but did not affect AMPK phosphorylation in mouse skeletal muscle (Lo et al. 2014). Moreover, an...
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파킨슨 병리 ... jama 논문.. 2024.07.10해당카페글 미리보기
in ARJP. Moreover, steady-state levels of the known parkin substrates were surprisingly unaltered in the parkin knockout mouse.7,8 Two-dimensional gel electrophoresis followed by mass spectrometry analysis revealed a decrease in the...
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만성염증 --> 자가면역 염증으로 진행하는 과정의 중요 인자 NF-κB 탐구!! 2024.07.04해당카페글 미리보기
to timing – that is, before, during, or after pre-antigen receptor signaling. Although no single NF-κB-subunit-knockout mouse has as severe a phenotype as NEMO knockouts with regard to the generation of mature lymphocytes, double...
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Re: 염증유발 과정에서 NF-κB signaling 탐구 .. 2024.07.04해당카페글 미리보기
β knockout mice are more sensitive to endotoxin shock.67 The negative role of IKKβ in inflammasome activation appears to involve induction of autophagy, an intracellular degradation system that maintains cellular homeostasis through...
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알레르기의 원인 '파발부민' 탐구 2024.06.30해당카페글 미리보기
OM knockout mice lose their hearing after 3–4 months. It was suggested that, in sensory cells, OM maintains auditory function, most likely affecting outer hair cells’ motility mechanisms. 파발부민(PA)은 EF-hand 수퍼패밀리에 속하는 작고...
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Regulation of Immune Function by the Lymphatic Vasculature 2024.06.25해당카페글 미리보기
to an increased risk of CD recurrence (47). A multitude of studies have been performed in mouse models of IBD, the two most-commonly used being IL-10 knockout mice and dextran sulfate sodium (DSS)-induced colitis. IL-10-deficient mice...