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Re: B 세포 교차반응 자가면역 질환들 RA, SLE, MS, 당뇨... 2024.06.30해당카페글 미리보기
stays in the host for life and shuttles between an active (lytic) and inactive state (latent) [17,29,35]. Upon EBV reactivation, the immune system may fight off EBV; however, in immune-compromised individuals, the reactivation of EBV is...
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안구건조, 입마름 쇼그렌 증후군 탐구!! 2024.06.28해당카페글 미리보기
trigger immune system activation to self-antigens in pSS. However, no correlation has been found between EBV reactivation periods and the development of pSS symptoms96; furthermore, the molecular mimicry hypothesis does not explain why...
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Re: B 세포 senescence 2024.06.28해당카페글 미리보기
infection in healthy individuals but may cause severe disease in immunocompromised hosts (Freeman 2009). The reactivation of CMV is induced by proinflammatory mediators. CMV infection rapidly induces the translocation of NF-κB into the...
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전정 신경염 2024.06.08해당카페글 미리보기
직접 변성이나 전전정동맥(anterior vestibular artery)의 허혈 등과 같은 가설이 제시되고 있으나, 잠복 바이러스의 재활성화(reactivation)에 의한 이차적인 면역반응에 의한 변성일 가능성이 높다. 증상 심한 어지럼증과 구역, 구토가 자연적으로 발생...
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운동으로 만성염증을 치료하는 방법에 관한 논문... 2024.04.26해당카페글 미리보기
and correlate with increased URTI incidence [101, 116,117,118]. Others, however, argue that the symptoms are in fact reactivation of a virus not completely cleared before running the race, or even non-infective inflammation as a result...
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Mitochondrial TCA cycle metabolites control physiology and disease 2024.02.15해당카페글 미리보기
fumarate and L-2-HG under normoxic conditions can inhibit PHDs31. Interestingly, in the opposite direction, the reactivation of PHDs by increased intracellular α-KG levels in hypoxic cancer cells causes a severe metabolic impairment...
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Re: 병든 세포의 제거와 수리, 리소좀 2024.02.02해당카페글 미리보기
acts as an amino sensor essential for the activation the mTORC1 pathway.54,56 The increase of nutrients can lead to the reactivation of mTORC1, thereby inhibiting the catabolic pathway and promoting substance synthesis and cell growth...
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Autophagy genes in biology and disease 2024.02.01해당카페글 미리보기
ALR)63 (Fig. 1a, ‘Recycling’). This process recycles lysosomal membrane proteins and is triggered by the reactivation of mTORC1 in response to increased amino acid levels owing to prolonged macroautophagy. Upon induction of ALR, the...
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Re: 비타민 D 결핍을 야기하는 약물들 2023.10.23해당카페글 미리보기
susceptibility to infection with TB has been reported to be associated with deficiency of vitamin D, as has reactivation of latent infections. As CYP3A4 is inhibited by isoniazid and induced by rifampicin, these drugs may affect vitamin...
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Re: 치매의 원인들 4-1. 환경호르몬 치매 유발기전 3 hit 이론!! 2023.09.02해당카페글 미리보기
assuming that early exposure leads to epigenomic regulations which could bring about AD occurrence after a reactivation event such as renewed exposure to pollutants, obesity or diabetes, chronic inflammation, and vascular dysfunctions...