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활성산소.. 적절함 redox biology 과함 oxidative stress.. Redox balance 2024.07.11해당카페글 미리보기
ERK to promote cell proliferation, nutrient uptake, and cell survival [18]. However, RTKs and PI3K are negatively regulated by protein-tyrosine phosphatases (PTPs) and PTEN, respectively, resulting in dampening of mitogenic signaling [19...
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Re: 파킨슨 자가면역염증 관련 ... 2022 Nature 논문.. 2024.07.11해당카페글 미리보기
neurotoxic microglia from patient-derived induced pluripotent stem cells79. Interestingly, LRRK2 is an IFNγ target gene regulated in immune cells in response to pathogens80,81,82; genetic polymorphisms in LRRK2 (discussed below) have been
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세포 찌거기 제거. 오토파지.. 운동으로 유도된다... 2024.07.10해당카페글 미리보기
degradation for up to 24 hours (Biolo et al. 1995; Phillips et al. 1997) underlining the importance of a well-regulated balance between protein synthesis and degradation in the regulation of muscle mass. Endurance exercise training...
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Re: 자가포식-리소좀 시스템 2020 nature 논문 . 2024.07.10해당카페글 미리보기
that V-ATPase inhibition did not affect the efflux of most essential amino acids, which was instead found to be regulated by mTORC1 activity in an SLC38A9-dependent manner53. Hence, catabolite efflux from lysosomes may be subjected to...
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Re: 자가포식-리소좀 시스템 --> 신경퇴행성 . 2024.07.10해당카페글 미리보기
may serve signaling or pathogenic functions. The ALP is active in healthy cells, and the level of activity can be regulated by nutrient-sensing and metabolic signaling pathways. The ALP is the primary pathway by which lipids and damaged...
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Re: 만성염증 자가면역 염증 전환 지점 탐구.. 자가반응 T 세포... 2024.07.08해당카페글 미리보기
1). Another issue comprises the presence of tissue-specific genes that are not expressed in the thymus and poorly regulated by the autoimmune regulator [AIRE, (2)], toward which T-cells are not depleted during thymic selection. As a...
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자율운항선박. 원격조종선박 2 - 해양대학교 2024.07.07해당카페글 미리보기
federal legislation provides that “pilots in the bays, rivers, harbors, and ports of the United States shall be regulated only in conformity with the laws of the States.’’ ☞ 그러나, 그 두 가지 예외(pilots와이즈 및 오대호 무역)를 제외...
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면역세포의 노화. 2023년 nature review 2024.07.06해당카페글 미리보기
for glucose between upregulated Tregs and effector T cells triggers ATM-related DNA damage, induces extracellular regulated protein kinases 1/2 (ERK1/2) and p38 pathways, and activates signal transducer and activator of transcription 1...
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Re: T 세포로 보는 자가면역으로 전환하는 시점 탐구!! 2023년 Nature 2024.07.06해당카페글 미리보기
induced by IL-2, TSLP, and TL1A promotes Th9 cell development.99 The differentiation of Th9 cells is also regulated by costimulation signaling (CD28, OX40, GITR, Notch, and DR3) and other cytokines (IL-1, IL-25, IL-7, and IL-21...
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스트레스 반응이 어떻게 자가면역 쇼그렌증후군을 일으키는가? 2024.07.05해당카페글 미리보기
translocation of secretory vesicles to the cell membrane, and exocytosis [26]. The watery component of saliva is regulated by signals from the parasympathetic nervous system through the action of acetylcholine (Ach) on the muscarinic...