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Re: 음식치료제 : 베타 하이드로뷰티레이트.. 항염증 효과 탐구!! 2024.07.17해당카페글 미리보기
ketogenesis does not influence the circulating ketone body concentration. Collectively, by controlling the substrate accession (mainly controlled by the ratio of insulin to glucagon) and strictly spatiotemporal expression of mHMGCS2...
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음식치료제 : 베타 하이드로뷰티레이트(케톤체) 탐구!! 2024.07.17해당카페글 미리보기
Such signaling metabolites include acetyl-CoA (coenzyme A), another carrier of high-energy bonds that is also substrate for a widely prevalent protein posttranslational modification (lysine acetylation), and S-adenosyl-methionine, which...
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산화질소 탐구!! 산소와 산화질소의 관계... 2024.07.17해당카페글 미리보기
can bind reversibly to the catalytic iron and inhibit a variety of these enzymes to varying degrees. As O2 is the normal substrate for these enzymes, the reaction of •NO at the iron site is competitive and it will depend on the relative...
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Re: 활성산소, Nitro oxidative stress 바이오 마커.... 2024.07.17해당카페글 미리보기
fluxes. Another aspect that is often neglected when addressing O2·‐ is the role of NO, which is the primary substrate of the original ROS, the superoxide anion O2 −. Indeed, the reaction rate of ·NO with O2 −, estimated at 9 × 109...
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Re: 면역 조절기능에서 대식세포의 역할 2023년 nature review 2024.07.16해당카페글 미리보기
achieved by macrophages to satisfy their crucial purpose in removing disease and remodeling tissues. The impact of substrate rigidity on macrophages’ phagocytic activity has been evaluated in several investigations. RAW 264.7...
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Re: Re: 활성산소의 지질(lipid) 손상에 대한 탐구!! 2024.07.16해당카페글 미리보기
position of acyl chains [40]. Arachidonate lipoxygenase-15 (Alox15) which encodes for the 12/15-LOX has a unique substrate requirement among the LOX family. It can directly oxygenate PUFA containing PLs without prior release of...
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Re: 활성산소의 단백질 손상 vs 유익함에 대한 탐구!! 2024.07.16해당카페글 미리보기
of adjacent basic amino acid residues [117], the microenvironment of the target cysteine residues [117], and substrate binding [119]. For example, albumin cysteine 34 has a very low pKa value of 5 [120]. Hence under physiological...
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면역반응의 산화, 환원 생리학!! 2022년 nature review 2024.07.15해당카페글 미리보기
of citrate into alpha-ketoglutarate via the action of cytosolic IDH [97, 98]. Cytosolic citrate is also a substrate of ACLY, producing acetyl-CoA and oxaloacetate and upregulating acetyl-CoA carboxylase (ACC) stimulating lipid synthesis...
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Re: 활성산소와 그 수치 검사 2022 nature ... 2024.07.14해당카페글 미리보기
by the growing literature on ferroptosis, a form of cell death involving ‘catalytic’ iron ions15. H2O2 is a substrate for haem peroxidases such as myeloperoxidase, generating further reactive species such as HOCl (Table 1). Despite its...
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세포 찌거기 제거. 오토파지.. 운동으로 유도된다... 2024.07.10해당카페글 미리보기
al. 2015), suggesting that activation of autophagy in skeletal muscle during exercise is not caused by insufficient substrate supply. 운동 유발 자가포식의 분자 매개체 AMPK AMP-activated protein kinase 세포 배양 연구에 따르면 5′ AMP...