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signatures.104,105,106,107 Incomplete removal of somatic cell-specific epigenetic signatures as well as aberrant de novo DNA methylation associated with reprogramming can affect the status and the differentiation potential of iPSCs...

from congenital disorders, with the most common forms being Milroy disease and distichiasis (which also causes aberrant eye-lashes). Both commonly affect the lower limbs, but Milroy is usually symmetrical and present at birth or soon...

nerve ends to healthy fascicular structures. The topographic anatomy must be restored to decrease the risk of aberrant reinnervation. 52 This can be achieved by realigning the vasa nervorum, and by visually identifying known fascicular...

directly oxidize macromolecules, including membrane lipids, structural proteins, enzymes and nucleic acids, leading to aberrant cell function and death. The second mechanism of oxidative stress is aberrant redox signalling (Box 2...