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feedback loop that amplifies the inflammatory response.112 Continuous activation of the NLRP3 inflammasome is associated with the pathogenesis of several inflammatory disorders, including Alzheimer’s disease, asthma and allergic airway...

inflammatory bowel disease (IBD), rheumatoid arthritis, and allergies [31,32]. SCFAs exert multiple beneficial effects on the immune system. SCFAs promote the differentiation of Tregs in the gut through histone deacetylase (HDAC...

and bowel movement regulation—holds promise in mitigating the CKD progression via the gut–kidney axis. Together, they represent a multifaceted approach to managing CKD progression, reducing inflammation, systemic toxicity and oxidative...

irritable bowel syndrome, primary headaches, pelvic pain, and vestibulodynia. COPCs are characterized by symptoms consistent with the dysregulation of sensory, inflammatory, and psychological domains13,56,59,60. There is increased...