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closed-loop system 구축. AI + real-world data + prospective validation 강화. 결론 및 의의 의학의 paradigm shift: “예측하고 예방한다”는 새로운 시대. Topol은 “forecasting medicine”을 실현하기 위해 기술·데이터·윤리적 도전을 강조. 이는...

feedback loop that amplifies the inflammatory response.112 Continuous activation of the NLRP3 inflammasome is associated with the pathogenesis of several inflammatory disorders, including Alzheimer’s disease, asthma and allergic airway...

inflammatory bowel disease (IBD), rheumatoid arthritis, and allergies [31,32]. SCFAs exert multiple beneficial effects on the immune system. SCFAs promote the differentiation of Tregs in the gut through histone deacetylase (HDAC...

and bowel movement regulation—holds promise in mitigating the CKD progression via the gut–kidney axis. Together, they represent a multifaceted approach to managing CKD progression, reducing inflammation, systemic toxicity and oxidative...