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保存 0 Timeline 文字 印刷 読者投稿0 アルツハイマー病症例の約10％に早い段階から生じる、後部皮質萎縮症（posterior cortical atrophy；PCA）と呼ばれる視覚障害は、近いうちにアルツハイマー病を発症することを知らせるシグナルである可能性の高いこ...

and cortical neurons (Cheah et al., 2006). Recently, we have shown that NO directly modulated DMT1 and enhanced its function via S-nitrosylation. This is unexpected as S-nitrosylation of proteins important in PD such as Parkin and XIAP...

this cortical network, the cingulate cortex innevates the upper face bilaterally and receives projetions from the limbic lobe and amydala, coveying emotional expressions to the facial muscles.47 In the differential diagnosis, tics must...

optic atrophy-1; PGC1α, peroxisome proliferator-activated receptor γ coactivator 1; mfn 1 and 2, mitofusin-1 and 2; NRF1 and 2, nuclear respiratory factor 1 and 2; ROS, reactive oxygen species; TFAM, transcription factor A; ΔΨ...

some cortical irregularities and labral ossifications that should not be confused with OA-related structural bone changes [41, 60, 61]. The radiographic JSW corresponds to the distance between the acetabular roof and the femoral head...

brain atrophy [3]. It is suggested that not all cathepsins, but only several, may compensate for each other in vivo. 켑신은 대부분의 세포에서 발견되는 엔도펩티다아제로, 세포 자가 분해와 조직의 자가 소화에 관여합니다. 켑신은 구조와 촉매...

denervation, atrophy of voluntary skeletal muscles, and ultimately paralysis and death. The worldwide incidence of ALS is estimated at ~5/100,000 (Chio et al., 2013). Onset is usually age-dependent, although rare genetic forms may have a...

gross atrophy of frontal and anterior temporal lobes (Brun, 1987; McKhann et al., 2001), and their histopathology reveals microvacuolar degeneration and loss of pyramidal neurons in the frontal and temporal cortex (Rabinovici and Miller...

and cortical calcifications rather than gastrointestinal-hindering diagnosis and management. We present a case of a young man with progressive neurologic symptoms and brain MR imaging findings worrisome for ALS. During the diagnostic...