cafe

68]. Growth factors like FGF9 further promote HAS2 expression through activation of the Wnt/β-catenin/TCF7L2 pathway, a critical signaling axis involved in development, tissue homeostasis, and disease [69,70]. The Wnt/β-catenin pathway...

studies showed that the rhythmic activation of the Unfolded Protein Response (UPR), a signal transduction pathway adjusting critical cellular function to the accumulation of proteins inside the endoplasmic reticulum (ER)49, plays a...

a critical regulator of vascular homeostasis, neurotransmission and host defence27,28. NO is an autocrine and paracrine signalling molecule whose lifetime and diffusion gradients are limited by scavenging reactions involving haemoglobin...

of smad2/3 mediated by binding to vitamin D receptors in nasal polyp-derived fibroblasts Smad2/3 signaling is a critical pathway induced by TGF-β1. Smad2/3 phosphorylation and translocation into the nucleus regulate α-SMA and...