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NAD+ can be generated in the mitochondria from NMNAT380, whose activity has been shown to be required in cells77, but dispensable in vivo as NAD+ can be replenished through other pathways such as import from the cytosol81. Cytosolic NAD...

for the immediate retrograde transport of another injury signalling protein, phosphorylated STAT3 (pSTAT3), but is dispensable for the transport of both JNK and STAT3 after the early injury stage63. Local alterations in the microtubule...

on its interaction with Rad55. Interestingly, Rad55 is neededfor Csm2 enrichment at ARS sites while being dispensable for Shu complex interaction with Mcm4. These results are consistent with those from the Prado laboratory showing that...

dispensable[없어도되는]

together with the unchanged physiological phenotype, could lead to the conclusion that neuronal GLT-1 may be dispensable and hence redundant. However, molecular studies have recently revealed that mice lacking neuronal GLT-1 display...

SF9 not a single one can be dispensable

The Political Economy of Indigenous Dispossession: Bare and Dispensable Lives in the Andes 9 October 2012 By Roger Merino Acuña “A free soci­ety requires cer­tain mor­als that in the last instance are reduced to the con­ser­va­tion of...

By STEVE LOHR Maybe Japan is not as crucial to the global supply chain as those first weeks after the earthquake made it seem. Consider the case of STMicroelectronics, Europe’s giant in the semiconductor business, which buys silicon...

vu s’aligner démocratie libérale et profits capitalistiques, il semblerait qu’aujourd’hui la démocratie paraisse dispensable, voire problématique, dans une optique de profit. Le retrait de la démocratie par les plus riches, ce...