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Introduction The Spinocerebellar ataxias (SCA) are a subset of hereditary cerebellar ataxias that are autosomal dominantly transmitted. They are progressive neurodegenerative diseases that share the clinical features of ataxia, which...

may differentiate into myogenic lineages, crucial for muscle regeneration (Figure 1) [48,54]. These cells are dominantly quiescent within their vascular niche but can be activated by muscle injury or other pathologic conditions leading...

it is important to consider a variety of factors. One such variable to consider is the choice of cell line9. As the dominantly expressed genes vary across cell lines, analysis across diverse cell lines essential for confirming the MOA of...

in motor and sensory fascicles ChAT is an enzyme synthesized within motor axons, and ChAT immunofluorescence is dominantly expressed in motor fascicles [25]. Our study showed that the area percentage of ChAT-labeled axons (red staining...