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170 µM37), although digestion of the extracellular matrix (ECM) in the target tissue may also be important upon extravasation and colonisation in the absence of appropriate nutrient supply. Tumours have therefore found means of utilising...

issues (75). In addition, SI joint block can be one of the most challenging spinal injection procedures. Extravasation of LA to surrounding pain-generating structures such as muscles, ligaments, and lumbosacral nerve roots can lead to...

vasoactive substances including CGRP and SP [66]. These neuropeptides contribute to vasodilation, plasma protein extravasation, mast cell activation, and the release of proinflammatory cytokines, resulting in a phenomenon called...

the involvement of T lymphocytes mediating FPIES reactions.41,42 Global activation of T lymphocytes and their extravasation from the peripheral blood after positive FPIES challenges are demonstrated through significant loss of...