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Re: neuronal cell death 기전 탐구!! 2021 nature 2024.08.11해당카페글 미리보기
of three subgroups based on their structure and function with the presence of conserved regions termed BCL-2 homology (BH) motifs). This includes the anti-apoptotic proteins (BCL-2, BCL-XL, MCL-1, BCL-W and A1/BFL1), the BH3-only...
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Re: glutamate receptor와 파킨슨 증상의 관계 탐구!! 2024.07.29해당카페글 미리보기
activity [7]. The mGluRs family can be further divided into eight receptor subtypes. Based on their sequence homology, signal transduction mechanisms, and pharmacological profile, these subtypes are classified into three groups. Group I...
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만성염증 --> 자가면역 염증으로 진행하는 과정의 중요 인자 NF-κB 탐구!! 2024.07.04해당카페글 미리보기
RelB (Figure 1). These transcription factors share an N-terminal DNA-binding/dimerization domain, known as the Rel homology domain, through which they can form homo- and heterodimers. NF-κB dimers can bind to a variety of related target...
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Re: B 세포 교차반응 자가면역 질환들 RA, SLE, MS, 당뇨... 2024.06.30해당카페글 미리보기
reported [82,83]. Cross-reactivity associated with molecular mimicry can be divided into subgroups: structural homology and sequence homology (Table 2) [7,41,84,85,86,87,88,89,90,91]. Sequence homology refers to % identified at the amino...
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입안의 세균(유익균)과 질병 - 2022년 nature review 2024.06.11해당카페글 미리보기
on the surface of macrophages to activate the TLR2/4 signaling pathway.167 Activated TLR2/4 can bind to the TIR homology domain and the N-terminal death domain of MyD88 to activate IRAK. The activated IRAK then binds to TNF receptor...