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of three subgroups based on their structure and function with the presence of conserved regions termed BCL-2 homology (BH) motifs). This includes the anti-apoptotic proteins (BCL-2, BCL-XL, MCL-1, BCL-W and A1/BFL1), the BH3-only...

activity [7]. The mGluRs family can be further divided into eight receptor subtypes. Based on their sequence homology, signal transduction mechanisms, and pharmacological profile, these subtypes are classified into three groups. Group I...

RelB (Figure 1). These transcription factors share an N-terminal DNA-binding/dimerization domain, known as the Rel homology domain, through which they can form homo- and heterodimers. NF-κB dimers can bind to a variety of related target...

reported [82,83]. Cross-reactivity associated with molecular mimicry can be divided into subgroups: structural homology and sequence homology (Table 2) [7,41,84,85,86,87,88,89,90,91]. Sequence homology refers to % identified at the amino...

on the surface of macrophages to activate the TLR2/4 signaling pathway.167 Activated TLR2/4 can bind to the TIR homology domain and the N-terminal death domain of MyD88 to activate IRAK. The activated IRAK then binds to TNF receptor...

homologs, including paralogs and orthologs, among the genes of several completely sequenced eukaryotic genomes. homology See homologous. homologous The term refers to similarity attributable to descent from a common ancestor. Homologous...

cells did not respond to subsequent TLR7 stimulation, due to elevated MyD88 pathway inhibitors: IRAK-M and Src homology 2 domain-containing inositol-5-phosphatase-1, and impaired activation of NF-κB, MAPK p38, and c-Jun N-terminal...

Keywords: gluten, nutrients, intestine, brain, neurodegeneration, gut-brain axis, cross-reactivity, sequence homology, BLAST 글루텐은 밀에 많이 들어있는 단백질이다. 글루텐은 몇몇 글루텐 의존성 질환뿐만 아니라 non-celiac 자가면역 질환도...

질문1 여러 유전자중 특정 유전자 발현 위해 특정 전사인자가 활성화 되야하는 것인데 (☆질문2 단 그 유전자는 insulator 안에 존재 해야하나요? insulator 안에 유전자가 여러개면 특정 전사인자가 활성화 되도 insulator 안의 유전자는 모두 발현되나요...