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of sHSPs to titin Ig domains in stretched myocytes appears to be triggered by the exposure of previously buried hydrophobic residues in the titin protein chain upon Ig domain unfolding (37). However, sHSPs such as CryaB may be able to...

the sequence motifs that have β-strand propensity, and are involved in the formation of cross-β fibrils, contain hydrophobic residues that mediate binding to the constitutively expressed Hsc70 chaperone (Mitul et al. 2008). Hsp70 also...

the nucleic acids (negatively charged and hydrophilic) into the carriers via electrostatic interactions and hydrophobic interactions [79]. In 2018, the modified mRNA molecule for expressing a desired anti-inflammatory cytokine (e.g., IL...

conserved structural motifs consisting of three amino acids each (clusters I and II), which contribute to the hydrophobic core of the EF-hand domains, have been revealed. Despite several decades of studies, physiological functions of PA...